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Ireland· IE-PA-PPA0465/091/005

Seretide 125 Evohaler 25 microgram/125 microgram/dose pressurised inhalation, suspension

A salmeterol and fluticasone product containing fluticasone propionate + salmeterol xinafoate, registered in Ireland by PCO Manufacturing Ltd.. The same ATC class is registered in 14 of our 19 countries.

ATC R03AK06

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedSeretide 125 Evohaler 25 microgram/12…ATCR03AK06REGISTER NO.IE-PA-PPA0465/091/005PACKS LISTED1CHECKEDSeptember 28, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about fluticasone propionate + salmeterol xinafoateAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Salmeterol and fluticasone is registered in 14 of 19 countries.

Countries holding a registration under ATC R03AK06 (salmeterol and fluticasone), each read from that country’s own register.

  • This record: Ireland, from HPRA (Ireland)
  • 9 of them publish a price we can compare per daily dose
Search salmeterol and fluticasone products by name

Salmeterol and fluticasone · ATC R03AK06

14 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

HPRA (Ireland)
Active substance
Fluticasone propionate + SALMETEROL XINAFOATE
Manufacturer
PCO Manufacturing Ltd.
Country
Ireland (IE)
ATC code
R03AK06
ATC class
Salmeterol and fluticasone
Defined daily dose
0.1 mg, Inhal
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    PPA0465/091/005

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

718 interactions on record for salmeterol and fluticasone.

Graded by severity as the source publishes them — 49 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check salmeterol and fluticasone against other medicinesHow interaction checks work

Salmeterol and fluticasone · interactions on record

718 records

  • 49 severe
  • 397 moderate
  • 24 minor
  • 248 info

Most severe, free to view

  • LonafarnibA16AX20severe
  • ConivaptanC03XA02severe
  • PindololC07AA03severe
  • PropranololC07AA05severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same class

Other records under R03AK06

Salmeterol and fluticasone, as other registers publish it.

All salmeterol and fluticasone products

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/75751fdd-a0ee-495d-b086-bbef0c4c9a86
GET /v1/drugs/75751fdd-a0ee-495d-b086-bbef0c4c9a86?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Pressurised inhalation, suspension",
  "routes": [
    "Inhalation use"
  ],
  "source": "hpra",
  "atc_all": [
    "R03AK",
    "R03AK06"
  ],
  "strength": null,
  "pa_number": "PPA0465/091/005",
  "substances": [
    "Fluticasone propionate",
    "SALMETEROL XINAFOATE"
  ],
  "legal_basis": "Parallel importation notified in accordance with Article 76(3) of Directive 2001/83/EC",
  "market_info": "Unknown",
  "authorised_at": "06/02/2004",
  "dispensing_status": "Product subject to prescription which may be renewed (B)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": "IC0128-176-053"
}
API referenceMCP serverPlans

See everything about salmeterol and fluticasone.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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