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United States · US · US:50419-491_9f4e7765-d4e7-4f36-9530-8b4444587214

Climara Pro

Orange BookUNIISPLATC G03CA

Last synced from FDA National Drug Code directory (United States) on

Identification

ManufacturerBayer HealthCare Pharmaceuticals Inc.
CountryUS (United States)
ATC codeG03CA
Dispensing
ReimbursedNo
SourceFDA National Drug Code directory (United States)
Last synced6/3/2026

Packs · 2

  • ndc11
    5041949104
    4 PATCH in 1 CARTON (50419-491-04) / 7 d in 1 PATCH
  • ndc11
    5041949173
    1 PATCH in 1 CARTON (50419-491-73) / 7 d in 1 PATCH

Annotations

UNII (FDA Substance ID)
4TI98Z838E
ESTRADIOL
RxCUI 4083
Orange Book
N021258
DailyMed SPL labels
1 version tracked
Raw payload (JSON)
{
  "unii": {
    "unii": "4TI98Z838E",
    "rxcui": "4083",
    "inchikey": "VOXZDWNPVJITMN-ZBRFXRBCSA-N",
    "display_name": "ESTRADIOL",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "TRANSDERMAL",
  "spl_meta": {
    "1e9702c4-f2d7-4ea8-b6e8-7dca31671864": {
      "match": "brand_token",
      "title": "CLIMARA (ESTRADIOL) PATCH [BAYER HEALTHCARE PHARMACEUTICALS INC.]",
      "spl_version": "25",
      "published_date": "2026-03-30"
    }
  },
  "productid": "50419-491_9f4e7765-d4e7-4f36-9530-8b4444587214",
  "productndc": "50419-491",
  "dosage_form": "PATCH",
  "orange_book": {
    "appl_no": "021258",
    "products": [
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "0.045MG/24HR;0.015MG/24HR",
        "product_no": "001",
        "approval_date": "Nov 21, 2003"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "ESTRADIOL; LEVONORGESTREL",
  "proprietary_name": "Climara Pro",
  "active_ingred_unit": "mg/d; mg/d",
  "application_number": "NDA021258",
  "marketing_category": "NDA",
  "nonproprietary_name": "Estradiol and Levonorgestrel",
  "start_marketing_date": "20031121",
  "active_numerator_strength": ".045; .015"
}

Related drugs

Other records sharing ATC code G03CA.

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