Spain· ES:64718
DUOFEMME COMPRIMIDOS RECUBIERTOS CON PELICULA.
A medicinal product containing noretisterona + estradiol, registered in Spain by Isdin S.A..
Checked against AEMPS CIMA (Spain) on
Informational only — not a medical device.
The record
At a glance
AEMPS CIMA (Spain)- Active substance
- noretisterona + estradiol
- Manufacturer
- Isdin S.A.
- Country
- Spain (ES)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- AEMPS CIMA (Spain)
- Last checked
- September 12, 2026
Packs & prices · 1
1 priced- cima_codigo72506928EUR 7.66
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Noretisterona + estradiol in 13 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClimesse tabletsMawdsley-Brooks & Company Ltd
- United StatesABIGALEXiromed LLC
- NorwayActivelleNovo Nordisk A/S
- SwitzerlandActivelle
- SwedenActivelle 1 mg/0,5 mg Filmdragerad tablettNovo Nordisk A/S
- PolandActivelleNovo Nordisk A/S
- IcelandActivelleNovo Nordisk A/S*
- FinlandCliovelleDr. Kade Pharmazeutische Fabrik GmbH
Authorised across Europe · EMA
The same active substance is authorised in 26 EEA countries. Names it is sold under:
- Austria · Activelle, Kliogest
- Belgium · Activelle, Activelle Minor
- Bulgaria · Активел, Трисеквенс
- Cyprus · Trisequens
- Czechia · Activelle, Kliogest
- Germany · Activelle, Cliovelle
- Denmark · Activelle, Activelle Low
- Estonia · Activelle, Eviana
- Finland · Activelle, Cliovelle
- France · Activelle, Kliogest
- Greece · Trisequens
- Croatia · Activelle, Novofem
- Hungary · Activelle, Kliogest
- Ireland · Activelle, Kliogest
- Iceland · Activelle, Activelle Low
- Italy · Activelle
- Lithuania · Activelle, Kliogest
- Luxembourg · Activelle, Activelle Minor
- Latvia · Activelle, Kliogest
- Netherlands · Activelle
- Norway · Activelle, Cliovelle
- Poland · Cliovelle, Kliogest
- Portugal · Activelle, Kliogest
- Sweden · Activelle, Cliovelle
- Slovenia · Activelle, Kliogest
- Slovakia · Activelle, Novofem
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of AEMPS CIMA (Spain). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/6da48c7a-1453-4914-a79b-c18b56eb0246 GET /v1/drugs/6da48c7a-1453-4914-a79b-c18b56eb0246?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cpresc": "Medicamento Sujeto A Prescripción Médica. Tratamiento De Larga Duración",
"estado": "{\"aut\":1019685600000}",
"nregistro": "64718",
"substance": "noretisterona + estradiol"
}See everything about noretisterona + estradiol.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.