Germany· DE-A57-960cd9d8bd20d2a8
Bis-Prenessa
A medicinal product containing bisoprolol fumarate, perindopril arginine, registered in Germany by Krka, D.D., Novo Mesto.
Checked against EMA Article 57 (European Union) on
Informational only — not a medical device.
The record
At a glance
EMA Article 57 (European Union)- Active substance
- Bisoprolol Fumarate, Perindopril Arginine
- Manufacturer
- Krka, D.D., Novo Mesto
- Country
- Germany (DE)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- EMA Article 57 (European Union)
- Last checked
- September 30, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Bisoprolol fumarate, perindopril arginine in 4 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaBIPRINDOKrka, d.d., Novo mesto, Novo mesto
- FinlandCosyrelLes Laboratoires Servier
- FranceCOSIMPREL 10 mg/10 mg, comprimé pelliculéLES LABORATOIRES SERVIER
- IrelandCosimprel 10mg/10mg Film-Coated TabletsLes Laboratoires Servier
Authorised across Europe · EMA
The same active substance is authorised in 19 EEA countries. Names it is sold under:
- Belgium · Bipressil
- Bulgaria · Би-Пренеса, Престилол
- Cyprus · Bi-Prenessa, Cosyrel
- Czechia · Bympero, Cosyrel
- Estonia · Prestilol
- France · Cosimprel
- Greece · Cosyrel
- Croatia · Bisonessa, Prestilol
- Hungary · Bihart, Cosyrel
- Ireland · Cosimprel
- Italy · Cosyrel
- Lithuania · Bisoprolol/Perindopril Arginine Krka, Bisoprolol/Perindopril Arginine Krka Krka
- Luxembourg · Bipressil
- Latvia · Asembix, Bisoprolol/Perindopril Arginine Krka
- Poland · Bympero, Prestilol
- Portugal · Cosyrel
- Romania · Cosyrel, Scaliant
- Slovenia · Bisonessa, Cosyrel
- Slovakia · Bi-Prenessa, Prestilol
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of EMA Article 57 (European Union). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/699d065f-5c4c-44c3-954d-f35675241a92 GET /v1/drugs/699d065f-5c4c-44c3-954d-f35675241a92?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"pzn": null,
"route": "Oral Use",
"source": "ema_art57_de",
"ma_number": null,
"substance": "Bisoprolol Fumarate, Perindopril Arginine",
"atc_from_source": null,
"authorisation_country": "Germany"
}See everything about bisoprolol fumarate, perindopril arginine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.