United States· US:71610-247_a3c90a47-42cb-44b6-99e0-f027dc45ac2b

Entacapone

A entacapone product containing entacapone, registered in United States by Aphena Pharma Solutions - Tennessee, LLC. The same ATC class is registered in 18 of our 19 countries.

ATC N04BX02US label

Checked against FDA National Drug Code directory (United States) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about entacaponeAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Entacapone is registered in 18 of 19 countries.

Countries holding a registration under ATC N04BX02 (entacapone), each read from that country’s own register.

This record: United States, from FDA National Drug Code directory (United States)
10 of them publish a price we can compare per daily dose

Search entacapone products by name

Entacapone · ATC N04BX02

18 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of entacapone costs, country by country.

Normalised to the WHO defined daily dose (1 g), the median price runs from $1.87 in France to $6.60 in Switzerland — a ×3.5 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Entacapone · price per daily dose (1 g)

USD · FX 28 Sept 2026

CH Switzerland$6.60
IT Italy$6.27
FR France$1.87

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)

Active substance: ENTACAPONE
Manufacturer: Aphena Pharma Solutions - Tennessee, LLC
Country: United States (US)
ATC code: N04BX02
ATC class: Entacapone
Defined daily dose: 1 g, O
Reimbursed: Not published by this register
Source register: FDA National Drug Code directory (United States)
Last checked: September 27, 2026

Packs & prices · 2

ndc11
7161024783
3600 TABLET, FILM COATED in 1 BOTTLE (71610-247-83)
ndc11
71610-247-83

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

110 interactions on record for entacapone.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check entacapone against other medicines How interaction checks work

Entacapone · interactions on record

110 records

2 severe
61 moderate
1 minor
46 info

Most severe, free to view

ProcarbazineL01XB01severe
Methylthioninium chlorideV03AB17severe
EpinephrineA01AD01moderate
MetoclopramideA03FA01moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Entacapone in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All entacapone products

Authorised across Europe · EMA

The same active substance is authorised in 16 EEA countries. Names it is sold under:

Cyprus · Encapia
Germany · Entacapon Hec
Denmark · Entacapone Viatris
Spain · Entacapona Viatris, Medapia
Finland · Entacapone Orion Pharma
France · Entacapone Arrow, Entacapone Viatris
United Kingdom (Northern Ireland) · Entacapone, Entacapone Hec
Croatia · Entakapon Hec
Iceland · Comtan, Comtess
Liechtenstein · Comtan, Comtess
Lithuania · Medapia
Malta · Medapia
Netherlands · Encapia, Entacapone Unichem
Norway · Comtan, Comtess
Portugal · Entacapona Aurobindo, Medapia
Sweden · Entacapone Viatris

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/682487b2-d307-4e3a-8d2e-a539db2e00c5
GET /v1/drugs/682487b2-d307-4e3a-8d2e-a539db2e00c5?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "ORAL",
  "source": "ndc",
  "strength": "200",
  "substance": "ENTACAPONE",
  "productndc": "71610-247",
  "dosage_form": "TABLET, FILM COATED",
  "dea_schedule": null,
  "strength_unit": "mg/1",
  "application_number": "NDA020796",
  "marketing_category": "NDA AUTHORIZED GENERIC"
}

API reference MCP server Plans

See everything about entacapone.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console