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Ireland· IE-PA-EU/1/16/1096/001-003

Lonsurf 15 mg/6.14 mg film-coated tablets

A trifluridin, kombinationen product containing trifluridine, registered in Ireland by Les Laboratoires Servier. The same ATC class is registered in 11 of our 19 countries.

ATC L01BC59

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedLonsurf 15 mg/6.14 mg film-coated tab…ATCL01BC59REGISTER NO.IE-PA-EU/1/16/1096/00…PACKS LISTED1CHECKEDSeptember 28, 2026

Where it is registered

Trifluridin, kombinationen is registered in 11 of 19 countries.

Countries holding a registration under ATC L01BC59 (trifluridin, kombinationen), each read from that country’s own register.

  • This record: Ireland, from HPRA (Ireland)
  • 7 of them publish a price we can compare per daily dose

Trifluridin, kombinationen · ATC L01BC59

11 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of trifluridin, kombinationen costs, country by country.

Normalised to the WHO defined daily dose (45 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Trifluridin, kombinationen · price per daily dose (45 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$126.56
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

HPRA (Ireland)
Active substance
Trifluridine
Manufacturer
Les Laboratoires Servier
Country
Ireland (IE)
ATC code
L01BC59
ATC class
Trifluridin, Kombinationen
Defined daily dose
45 mg, O
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    EU/1/16/1096/001-003

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

72 interactions on record for trifluridin, kombinationen.

Graded by severity as the source publishes them — 29 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Trifluridin, kombinationen · interactions on record

72 records

  • 29 severe
  • 43 moderate

Most severe, free to view

  • CladribineL01BB04severe
  • Talimogene laherparepvecL01XL02severe
  • Talimogen laherparepvecL01XX51severe
  • LeflunomidL04AA13severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Trifluridin, kombinationen in 5 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All trifluridin, kombinationen products

Authorised across Europe · EMA

The same active substance is authorised in 1 EEA country. Names it is sold under:

  • France · Virophta

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/60b4b55e-3a8b-4914-ac4a-6619d72a965e
GET /v1/drugs/60b4b55e-3a8b-4914-ac4a-6619d72a965e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Film-coated tablet",
  "routes": [
    "Oral use"
  ],
  "source": "hpra",
  "atc_all": [
    "L01BC",
    "L01BC59"
  ],
  "strength": null,
  "pa_number": "EU/1/16/1096/001-003",
  "substances": [
    "Trifluridine"
  ],
  "legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
  "market_info": "Unknown",
  "authorised_at": "25/04/2016",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

See everything about trifluridin, kombinationen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.