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United States· US:72189-563_4d3a9c67-ae9c-d4c1-e063-6394a90aff1f

Nortriptyline HCL

A nortriptyline product containing nortriptyline hcl, registered in United States by Direct_rx. The same ATC class is registered in 14 of our 19 countries.

ATC N06AA10Orange BookUS label

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedNortriptyline HCLATCN06AA10REGISTER NO.US:72189-563_4d3a9c67…PACKS LISTED1CHECKEDSeptember 12, 2026

Where it is registered

Nortriptyline is registered in 14 of 19 countries.

Countries holding a registration under ATC N06AA10 (nortriptyline), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 8 of them publish a price we can compare per daily dose

Nortriptyline · ATC N06AA10

14 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of nortriptyline costs, country by country.

Normalised to the WHO defined daily dose (75 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Nortriptyline · price per daily dose (75 mg)

USD · FX 28 Sept 2026

  • IT Italy$0.46
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
Nortriptyline HCL
Manufacturer
Direct_rx
Country
United States (US)
ATC code
N06AA10
ATC class
Nortriptyline
Defined daily dose
75 mg, O
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 12, 2026

Packs & prices · 1

  • ndc11
    7218956330
    30 CAPSULE in 1 BOTTLE, PLASTIC (72189-563-30)

Regulatory notes

UNII (FDA substance ID)
00FN6IH15D
NORTRIPTYLINE HYDROCHLORIDE
RxCUI 203130
Orange Book
A073556
ABABABAB
DailyMed SPL labels
1 version tracked

Interactions

481 interactions on record for nortriptyline.

Graded by severity as the source publishes them — 64 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Nortriptyline · interactions on record

481 records

  • 64 severe
  • 229 moderate
  • 16 minor
  • 91 info

Most severe, free to view

  • PapaverineA03AD01severe
  • CisaprideA03FA02severe
  • OndansetronA04AA01severe
  • GranisetronA04AA02severe

81 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Nortriptyline in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All nortriptyline products

Authorised across Europe · EMA

The same active substance is authorised in 17 EEA countries. Names it is sold under:

  • Belgium · Nortrilen
  • Czechia · Nortrilen
  • Denmark · Noritren, Nortriptylin
  • Estonia · Noritren
  • Spain · Norfenazin 10 Mg Comprimidos, Norfenazin 25 Mg Comprimidos
  • Finland · Noritren
  • United Kingdom (Northern Ireland) · Nortriptyline, Nortriptyline 25mg Film-Coated Tablets
  • Ireland · Nortriptyline Pharmafile
  • Iceland · Noritren
  • Italy · Norcapto, Noritren
  • Lithuania · Noritren
  • Latvia · Noritren
  • Malta · Norterol, Nortrilen
  • Netherlands · Nortrilen, Nortriptyline Bb
  • Norway · Noritren
  • Portugal · Norterol, Nortriptilina Tecnifar
  • Sweden · Sensaval

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/5c365609-3183-4dc2-bbc9-2313be4bea9e
GET /v1/drugs/5c365609-3183-4dc2-bbc9-2313be4bea9e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unii": {
    "unii": "00FN6IH15D",
    "rxcui": "203130",
    "inchikey": "SHAYBENGXDALFF-UHFFFAOYSA-N",
    "display_name": "NORTRIPTYLINE HYDROCHLORIDE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "livertox": {
    "summary": null,
    "livertox_id": null,
    "hepatotoxicity_score": 3
  },
  "spl_meta": {
    "21770082-7a99-520d-e063-6394a90ab9cb": {
      "match": "brand_token",
      "title": "NORTRIPTYLINE HYDROCHLORIDE CAPSULE [ST. MARY'S MEDICAL PARK PHARMACY]",
      "spl_version": "4",
      "published_date": "2026-05-21"
    }
  },
  "productid": "72189-563_4d3a9c67-ae9c-d4c1-e063-6394a90aff1f",
  "productndc": "72189-563",
  "dosage_form": "CAPSULE",
  "orange_book": {
    "appl_no": "073556",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 75MG BASE",
        "product_no": "001",
        "approval_date": "Mar 30, 1992"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 10MG BASE",
        "product_no": "002",
        "approval_date": "Mar 30, 1992"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 25MG BASE",
        "product_no": "003",
        "approval_date": "Mar 30, 1992"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 50MG BASE",
        "product_no": "004",
        "approval_date": "Mar 30, 1992"
      }
    ],
    "appl_type": "A"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "NORTRIPTYLINE HYDROCHLORIDE",
  "proprietary_name": "Nortriptyline HCL",
  "active_ingred_unit": "mg/1",
  "application_number": "ANDA073556",
  "marketing_category": "ANDA",
  "nonproprietary_name": "Nortriptyline HCL",
  "start_marketing_date": "20240626",
  "active_numerator_strength": "10"
}

See everything about nortriptyline.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.