Poland· PL-100396213
Ayupil
A clozapine product containing clozapinum, registered in Poland by Synthon B.V.. The same ATC class is registered in 17 of our 19 countries.
Checked against URPL (Poland) on
Informational only — not a medical device.
Where it is registered
Clozapine is registered in 17 of 19 countries.
Countries holding a registration under ATC N05AH02 (clozapine), each read from that country’s own register.
- This record: Poland, from URPL (Poland)
- 10 of them publish a price we can compare per daily dose
Clozapine · ATC N05AH02
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of clozapine costs, country by country.
Normalised to the WHO defined daily dose (0.3 g), the median price runs from $1.63 in France to $2.78 in Switzerland — a ×1.7 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Clozapine · price per daily dose (0.3 g)
USD · FX 28 Sept 2026
- CH Switzerland$2.78
- IT Italy$2.38
- FR France$1.63
The record
At a glance
URPL (Poland)- Active substance
- Clozapinum
- Manufacturer
- Synthon B.V.
- Country
- Poland (PL)
- ATC code
- N05AH02
- ATC class
- Clozapine
- Defined daily dose
- 0.3 g, O
- Reimbursed
- Not published by this register
- Source register
- URPL (Poland)
- Last checked
- September 27, 2026
Packs & prices · 36
- gtin05909991407919
- gtin05909991407926
- gtin05909991407933
- gtin05909991407940
- gtin05909991407957
- gtin05909991407964
- gtin05909991407971
- gtin05909991407988
- gtin05909991407995
- gtin05909991408008
- gtin05909991408015
- gtin05909991408022
- gtin05909991408039
- gtin05909991408046
- gtin05909991408053
- gtin05909991408114
- gtin05909991408121
- gtin05909991408138
- gtin05909991408435
- gtin05909991407797
- gtin05909991407803
- gtin05909991407810
- gtin05909991407827
- gtin05909991407834
- gtin05909991407841
- gtin05909991407858
- gtin05909991407865
- gtin05909991407872
- gtin05909991407889
- gtin05909991407896
- gtin05909991407902
- gtin05909991408060
- gtin05909991408077
- gtin05909991408084
- gtin05909991408091
- gtin05909991408107
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
620 interactions on record for clozapine.
Graded by severity as the source publishes them — 306 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Clozapine · interactions on record
620 records
- 306 severe
- 197 moderate
- 4 minor
- 61 info
Most severe, free to view
- PapaverineA03AD01severe
- MetoclopramideA03FA01severe
- CisaprideA03FA02severe
- OndansetronA04AA01severe
52 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Clozapine in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClozapine 12.5mg orodispersible tablets sugar freeViatris UK Healthcare Ltd
- IrelandClozaril 12.5 mg orodispersible tabletsViatris Healthcare Limited
- United StatesClozapineTeva Pharmaceuticals USA, Inc.
- NetherlandsAyupine 100 mg, orodispergeerbare tablettenSynthon B.V.
- FinlandClozapin HexalHexal A/S
- CzechiaCLOZAPIN DESITINDesitin Arzneimittel GmbH, Hamburg
- SpainAGAVAN 100 MG COMPRIMIDOS EFGAristo Pharma Gmbh
- FranceCLOZAPINE ACCORD 100 mg, comprimé sécableACCORD HEALTHCARE FRANCE
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Clozapin Accord, Clozapin Ratiopharm
- Belgium · Clozapine Sandoz, Leponex
- Bulgaria · Ексклоза, Клозапин Акорд
- Cyprus · Clozapine Accord, Clozarem
- Czechia · Clozapin Desitin, Leponex
- Germany · Clozapin 1a-Pharma, Clozapin Abz
- Denmark · Clozapin Accord, Clozapin Hexal
- Estonia · Clozapine Accord, Leponex
- Spain · Clozabrain, Clozapina Aurovitas
- Finland · Clozapine Accord, Clozapine Stada
- France · Clozapine Accord, Clozapine Aristo
- United Kingdom (Northern Ireland) · Clozapine, Clozapine Viatris
- Greece · Leponex
- Croatia · Klozapin Accord, Klozapin Alpha-Medical
- Hungary · Clozapine Gerot, Clozapine Stada
- Ireland · Clozaril, Denzapine
- Iceland · Clozapin Medical, Clozapine Actavis
- Italy · Clozapina Accord, Clozapina Aurobindo
- Lithuania · Clozapine Accord, Leponex
- Luxembourg · Leponex
- Latvia · Clozapine Accord, Leponex
- Malta · Clozarem
- Netherlands · Ayupine, Clozapine Accord
- Norway · Clozapin Hexal, Clozapine Accord
- Portugal · Clozapina Aristo, Clozapina Aurovitas
- Romania · Leponex
- Sweden · Clozapine Accord, Clozapine Actavis
- Slovenia · Klozapin Accord, Leponex
- Slovakia · Clozapine Accord, Leponex
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/5b199f9f-824e-4b83-82e8-60ec93142081 GET /v1/drugs/5b199f9f-824e-4b83-82e8-60ec93142081?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tabletki ulegające rozpadowi w jamie ustnej",
"source": "urpl",
"strength": "12,5 mg",
"packaging": "05909991407797 ¦ Rp ¦ 133200\n7 tabl. w blistrze\n05909991407803 ¦ Rp ¦ 133201\n10 tabl. w blistrze\n05909991407810 ¦ Rp ¦ 133202\n14 tabl. w blistrze\n05909991407827 ¦ Rp ¦ 133203\n20 tabl. w blistrze\n05909991407834 ¦ Rp ¦ 133204\n28 tabl. w blistrze\n05909991407841 ¦ Rp ¦ 133205\n30 tabl. w blistrze\n05909991407858 ¦ Rp ¦ 133206\n40 tabl. w blistrze\n05909991407865 ¦ Rp ¦ 133207\n50 tabl. w blistrze\n05909991407872 ¦ Rp ¦ 133208\n56 tabl. w blistrze\n05909991407889 ¦ Rp ¦ 133209\n60 tabl. w blistrze\n05909991407896 ¦ Rp ¦ 133210\n84 tabl. w blistrze\n05909991407902 ¦ Rp ¦ 133211\n90 tabl. w blistrze\n05909991407919 ¦ Rp ¦ 133212\n100 tabl. w blistrze\n05909991407926 ¦ Rp ¦ 133213\n250 tabl. w blistrze\n05909991407933 ¦ Rp ¦ 133214\n300 tabl. w blistrze\n05909991407940 ¦ Rp ¦ 133215\n500 tabl. w blistrze\n05909991407957 ¦ Rp ¦ 133216\n7 tabl. w blistrze perforowanym\n05909991407964 ¦ Rp ¦ 133217\n10 tabl. w blistrze perforowanym\n05909991407971 ¦ Rp ¦ 133218\n14 tabl. w blistrze perforowanym\n05909991407988 ¦ Rp ¦ 133219\n20 tabl. w blistrze perforowanym\n05909991407995 ¦ Rp ¦ 133220\n28 tabl. w blistrze perforowanym\n05909991408008 ¦ Rp ¦ 133221\n30 tabl. w blistrze perforowanym\n05909991408015 ¦ Rp ¦ 133222\n40 tabl. w blistrze perforowanym\n05909991408022 ¦ Rp ¦ 133223\n50 tabl. w blistrze perforowanym\n05909991408039 ¦ Rp ¦ 133224\n56 tabl. w blistrze perforowanym\n05909991408046 ¦ Rp ¦ 133225\n60 tabl. w blistrze perforowanym\n05909991408053 ¦ Rp ¦ 133226\n84 tabl. w blistrze perforowanym\n05909991408060 ¦ Rp ¦ 133227\n90 tabl. w blistrze perforowanym\n05909991408077 ¦ Rp ¦ 133228\n98 tabl. w blistrze perforowanym\n05909991408084 ¦ Rp ¦ 133229\n100 tabl. w blistrze perforowanym\n05909991408091 ¦ Rp ¦ 133230\n250 tabl. w butelce\n05909991408107 ¦ Rp ¦ 133231\n250 tabl. w blistrze perforowanym\n05909991408114 ¦ Rp ¦ 133232\n500 tabl. w butelce\n05909991408121 ¦ Rp ¦ 133233\n300 tabl. w blistrze perforowanym\n05909991408138 ¦ Rp ¦ 133234\n500 tabl. w blistrze perforowanym\n05909991408435 ¦ Rp ¦ 133295\n98 tabl. w blistrze",
"substance": "Clozapinum 12,5 mg",
"common_name": "Clozapinum",
"pl_product_id": "100396213",
"pozwolenie_nr": "25450",
"auth_procedure": "DCP",
"authorisation_validity": "2024-11-04"
}See everything about clozapine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.