Netherlands· NL-82df97b0e262
Dolten 50 mg filmomhulde tabletten
A tapentadol product containing tapentadolhydrochloride, registered in Netherlands by Medochemie Limited. The same ATC class is registered in 17 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Tapentadol is registered in 17 of 19 countries.
Countries holding a registration under ATC N02AX06 (tapentadol), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 10 of them publish a price we can compare per daily dose
Tapentadol · ATC N02AX06
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of tapentadol costs, country by country.
Normalised to the WHO defined daily dose (0.4 g), the median price runs from $2.14 in Italy to $6.62 in Switzerland — a ×3.1 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Tapentadol · price per daily dose (0.4 g)
USD · FX 28 Sept 2026
- CH Switzerland$6.62
- ES Spain$3.34
- IT Italy$2.14
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- TAPENTADOLHYDROCHLORIDE
- Manufacturer
- Medochemie Limited
- Country
- Netherlands (NL)
- ATC code
- N02AX06
- ATC class
- Tapentadol
- Defined daily dose
- 0.4 g, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id129332
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
184 interactions on record for tapentadol.
Graded by severity as the source publishes them — 30 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Tapentadol · interactions on record
184 records
- 30 severe
- 130 moderate
Most severe, free to view
- OndansetronA04AA01severe
- GranisetronA04AA02severe
- DolasetronA04AA04severe
- PalonosetronA04AA05severe
24 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Tapentadol in 15 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaPALEXIAGrünenthal GmbH, Aachen
- United StatesNucyntaCollegium Pharmaceutical, Inc.
- SpainPALEXIA 50 mg COMPRIMIDOS RECUBIERTOS CON PELICULAGrünenthal Pharma S.A.
- FinlandPalexiaGrünenthal GmbH
- BelgiumPalexia 50 mgGrunenthal
- NorwayPalexiaGrünenthal GmbH
- SwedenPalexia 50 mg Filmdragerad tablettGrünenthal GmbH
- IrelandPalexia 50 mg film-coated tabletsGrunenthal Pharma Limited.
Authorised across Europe · EMA
The same active substance is authorised in 24 EEA countries. Names it is sold under:
- Austria · Palexia, Palexia Retard
- Belgium · Palexia, Palexia Retard
- Cyprus · Dolten, Dolten Retard
- Czechia · Apeneta, Dolupren
- Germany · Palexia, Palexia Akutschmerz
- Denmark · Palexia, Palexia Depot
- Estonia · Tapemed Retard
- Spain · Palexia, Palexia Retard
- United Kingdom (Northern Ireland) · Ationdo, Ationdo Sr
- Greece · Dolupren, Dolupren Ir
- Croatia · Apeneta, Dolten
- Hungary · Adoben
- Ireland · Apeneta, Palexia
- Iceland · Tapentadol Stada
- Italy · Palexia, Taboxea
- Luxembourg · Palexia, Palexia Retard
- Malta · Dolten, Dolten Retard
- Norway · Palexia, Palexia Depot
- Poland · Adoben, Binatta
- Portugal · Ationdo, Palexia
- Romania · Dolten
- Sweden · Palexia, Palexia Depot
- Slovenia · Apeneta, Palexia
- Slovakia · Apeneta, Dolten
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/5ae966b5-48f8-4d7f-82e8-48d6c5b7c58e GET /v1/drugs/5ae966b5-48f8-4d7f-82e8-48d6c5b7c58e?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Filmomhulde tablet",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h129332_smpc_en.pdf",
"strength": null,
"atc_label": "Tapentadol",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg129332",
"excipients": [
"CELLULOSE, MICROKRISTALLIJN (E 460(i))",
"CROSCARMELLOSE NATRIUM (E 468)",
"LACTOSE 1-WATER",
"MACROGOL 3350",
"MAGNESIUMSTEARAAT (E 470b)",
"POLYVINYLALCOHOL (E 1203)",
"POVIDON K 30 (E 1201)",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)"
],
"substances": [
"TAPENTADOLHYDROCHLORIDE"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h129332_piluk.pdf",
"authorised_at": "2023/02/20",
"procedure_number": "NL/H/5529/001",
"dispensing_status": "Uitsluitend recept",
"registration_number": "129332",
"additional_monitoring": "N"
}See everything about tapentadol.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.