Canada· CA-DIN-00012750
MATULANE
A procarbazine product containing procarbazine (procarbazine hydrochloride), registered in Canada by LEADIANT BIOSCIENCES, INC. The same ATC class is registered in 10 of our 19 countries.
Checked against Health Canada Drug Product Database (Canada) on
Informational only — not a medical device.
Where it is registered
Procarbazine is registered in 10 of 19 countries.
Countries holding a registration under ATC L01XB01 (procarbazine), each read from that country’s own register.
- This record: Canada, from Health Canada Drug Product Database (Canada)
- 6 of them publish a price we can compare per daily dose
Procarbazine · ATC L01XB01
10 / 19 countries
- Canada
- Finlandprice
- Franceprice
- Germany
- Italyprice
- Netherlands
- Norwayprice
- Switzerlandprice
- United Kingdom
- United Statesprice
The record
At a glance
Health Canada Drug Product Database (Canada)- Active substance
- PROCARBAZINE (PROCARBAZINE HYDROCHLORIDE)
- Manufacturer
- LEADIANT BIOSCIENCES, INC
- Country
- Canada (CA)
- ATC code
- L01XB01
- ATC class
- Procarbazine
- Reimbursed
- Not published by this register
- Source register
- Health Canada Drug Product Database (Canada)
- Last checked
- October 1, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
470 interactions on record for procarbazine.
Graded by severity as the source publishes them — 168 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Procarbazine · interactions on record
470 records
- 168 severe
- 286 moderate
- 16 minor
Most severe, free to view
- IsomethepteneA03AX10severe
- OndansetronA04AA01severe
- GranisetronA04AA02severe
- DolasetronA04AA04severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Procarbazine in 9 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomProcarbazine 50mg capsulesA A H Pharmaceuticals Ltd
- SwitzerlandNatulan, capsule rigideCD PHARMA (SUISSE) SA
- FranceNATULAN 50 mg, géluleLEADIANT (ALLEMAGNE)
- NetherlandsNatulan, capsules, hard 50 mgLeadiant Biosciences Ireland Limited
- NorwayNatulan cd pharmaceuticalsLeadiant
- United StatesMatulaneLeadiant Biosciences, Inc.
- GermanyNatulanLeadiant Gmbh
- SpainNATULAN 50 MG CÁPULAS DURASLeadiant Biosciences Ireland Limited
Authorised across Europe · EMA
The same active substance is authorised in 6 EEA countries. Names it is sold under:
- Germany · Natulan
- Spain · Natulan
- France · Natulan
- United Kingdom (Northern Ireland) · Procarbazine Alliance Pharmaceuticals, Procarbazine Universal Medicines
- Italy · Natulan
- Netherlands · Natulan
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/5a92738c-c911-4889-b4a8-0cd797e46846 GET /v1/drugs/5a92738c-c911-4889-b4a8-0cd797e46846?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"din": "00012750",
"form": "CAPSULE",
"class": "Human",
"routes": [
"ORAL"
],
"source": "health_canada_dpd",
"status": "MARKETED",
"atc_raw": "L01XB01",
"schedule": [
"Prescription"
],
"drug_code": "938",
"strengths": [
"50 MG"
],
"ahfs_class": null,
"substances": [
"PROCARBAZINE (PROCARBAZINE HYDROCHLORIDE)"
],
"product_categorization": null
}See everything about procarbazine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.