Ireland· IE-PA-PA25244/001/002

Espestesin 40 mg/ml + 5 microgram/ml solution for injection

A articain, kombinationen product containing articaine hydrochloride + epinephrine, registered in Ireland by Pierrel S.p.A.. The same ATC class is registered in 11 of our 19 countries.

ATC N01BB58

Checked against HPRA (Ireland) on September 28, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about articaine hydrochloride + epinephrineAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Articain, kombinationen is registered in 11 of 19 countries.

Countries holding a registration under ATC N01BB58 (articain, kombinationen), each read from that country’s own register.

This record: Ireland, from HPRA (Ireland)
7 of them publish a price we can compare per daily dose

Search articain, kombinationen products by name

Articain, kombinationen · ATC N01BB58

11 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

HPRA (Ireland)

Active substance: Articaine hydrochloride + Epinephrine
Manufacturer: Pierrel S.p.A.
Country: Ireland (IE)
ATC code: N01BB58
ATC class: Articain, Kombinationen
Reimbursed: Not published by this register
Source register: HPRA (Ireland)
Last checked: September 28, 2026

Packs & prices · 1

ie_pa_number
PA25244/001/002

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

22 interactions on record for articain, kombinationen.

Graded by severity as the source publishes them — 21 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check articain, kombinationen against other medicines How interaction checks work

Articain, kombinationen · interactions on record

22 records

21 moderate
1 minor

Most severe, free to view

LidocainA01AE01moderate
TetracainA01AE02moderate
LidocaineC05AD01moderate
TetracaineC05AD02moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Articain, kombinationen in 10 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All articain, kombinationen products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Artinibsa, Orabloc
Belgium · Loncarti, Septanest Normal
Bulgaria · Normocain, Дентокаин
Cyprus · Dentocaine, Topicainol
Czechia · Septanest, Supracain
Germany · Artinestol, Artinestol 1:200.000
Denmark · Dentocaine, Norardent
Estonia · Dentocaine, Septanest
Spain · Articaina/ Epinefrina Dermogen, Articaína/Epinefrina Normon
Finland · Dentocaine, Norardent
France · Alphacaine N, Alphacaine Sp
United Kingdom (Northern Ireland) · Anestadent, Orabloc
Greece · Orabloc
Croatia · Septanest, Septanest Forte
Hungary · Septanest, Sylanest
Iceland · Artident
Italy · Citocartin Adrenalina
Lithuania · Citocartin, Dentocaine
Luxembourg · Loncarti, Septanest
Latvia · Dentocaine, Septanest
Malta · Dentocaine
Netherlands · Citocartin, Loncarti
Norway · Norardent, Septocaine
Poland · Citocartin 100, Citocartin 200
Portugal · Articaína + Adrenalina Normon, Artinibsa
Romania · Normocain, Orabloc
Sweden · Norardent, Nordanest
Slovenia · Septanestepi, Septanestepi V 1 Ml
Slovakia · Orabloc, Orabloc Forte

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/5a43fd2c-a0ef-4132-aa9d-84deeb0e577e
GET /v1/drugs/5a43fd2c-a0ef-4132-aa9d-84deeb0e577e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Solution for injection",
  "routes": [
    "Dental use"
  ],
  "source": "hpra",
  "atc_all": [
    "N01BB",
    "N01BB58"
  ],
  "strength": null,
  "pa_number": "PA25244/001/002",
  "substances": [
    "Articaine hydrochloride",
    "Epinephrine"
  ],
  "legal_basis": "Well-established use application (Article 10a of Directive No 2001/83/EC)",
  "market_info": "Not marketed",
  "authorised_at": "21/02/2003",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

API reference MCP server Plans

See everything about articain, kombinationen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console