United States· US:0280-0084_414c4b16-847c-79f9-e063-6394a90a40bd

Alka-Seltzer Hangover Relief

A medicinal product containing caffeine; aspirin, registered in United States by Bayer HealthCare LLC..

US label

Checked against FDA National Drug Code directory (United States) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about caffeine; aspirinAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

The record

At a glance

FDA National Drug Code directory (United States)

Active substance: CAFFEINE; ASPIRIN
Manufacturer: Bayer HealthCare LLC.
Country: United States (US)
ATC code: —
Reimbursed: Not published by this register
Source register: FDA National Drug Code directory (United States)
Last checked: September 27, 2026

Packs & prices · 12

ndc11
0280-0084-05
ndc11
0280-0084-06
ndc11
0280008401
10 POUCH in 1 CARTON (0280-0084-01) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280008402
18 POUCH in 1 CARTON (0280-0084-02) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280008403
60 POUCH in 1 CARTON (0280-0084-03) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280008404
2 POUCH in 1 CARTON (0280-0084-04) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280008405
1600 POUCH in 1 BOX (0280-0084-05) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280008406
30 POUCH in 1 CARTON (0280-0084-06) / 2 TABLET, EFFERVESCENT in 1 POUCH
ndc11
0280-0084-01
ndc11
0280-0084-02
ndc11
0280-0084-03
ndc11
0280-0084-04

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Same medicine, other countries

Caffeine; aspirin in 11 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All caffeine; aspirin products

Authorised across Europe · EMA

The same active substance is authorised in 16 EEA countries. Names it is sold under:

Austria · Acedol
Belgium · Aspirine Cafeine
Czechia · Acylcoffin
Germany · Aspirin Coffein, Doppel Spalt Compact
Denmark · Treo, Treo Citrus
Spain · Aspirina Plus, Cafiaspirina
Finland · Treo
France · Aspro Cafeine
United Kingdom (Northern Ireland) · Anadin Original, Beechams
Hungary · Aspicont
Ireland · Anadin Analgesic, Anadin Maximum Strength
Iceland · Treo, Treo Citrus
Luxembourg · Aspirine Cafeine
Poland · Coffepirine Tabletki Od Bólu Głowy, Dampiryna
Portugal · Melhoral, Salicylcafeina
Sweden · Bamyl Koffein, Fyro

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/556a92e4-4fcc-4492-9917-904512f7fb02
GET /v1/drugs/556a92e4-4fcc-4492-9917-904512f7fb02?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "ORAL",
  "source": "ndc",
  "strength": "65; 500",
  "substance": "CAFFEINE; ASPIRIN",
  "productndc": "0280-0084",
  "dosage_form": "TABLET, EFFERVESCENT",
  "dea_schedule": null,
  "strength_unit": "mg/1; mg/1",
  "application_number": "M013",
  "marketing_category": "OTC MONOGRAPH DRUG"
}

API reference MCP server Plans

See everything about caffeine; aspirin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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