Netherlands· NL-0f6b75e23fb8
Efracea, capsules met gereguleerde afgifte, hard 40 mg
A doxycycline product containing doxycycline 1-water, registered in Netherlands by Galderma Benelux B.V.. The same ATC class is registered in 16 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Doxycycline is registered in 16 of 19 countries.
Countries holding a registration under ATC J01AA02 (doxycycline), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 9 of them publish a price we can compare per daily dose
Doxycycline · ATC J01AA02
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of doxycycline costs, country by country.
Normalised to the WHO defined daily dose (0.1 g), the median price runs from $0.27 in Italy to $1.54 in Switzerland — a ×5.8 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Doxycycline · price per daily dose (0.1 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.54
- CZ Czechia$0.98
- IT Italy$0.27
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- DOXYCYCLINE 1-WATER
- Manufacturer
- Galderma Benelux B.V.
- Country
- Netherlands (NL)
- ATC code
- J01AA02
- ATC class
- Doxycycline
- Defined daily dose
- 0.1 g, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id33759
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
613 interactions on record for doxycycline.
Graded by severity as the source publishes them — 11 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Doxycycline · interactions on record
613 records
- 11 severe
- 143 moderate
- 35 minor
- 368 info
Most severe, free to view
- MipomersenC10AX11severe
- LomitapideC10AX12severe
- AcitretinD05BB02severe
- IsotretinoinD10AD04severe
56 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Doxycycline in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- PolandEfraceaInPharm Sp. z o.o.
- United KingdomEfracea 40mg modified-release capsulesWaymade Healthcare Plc
- IrelandEFRACEA 40 mg modified-release hard capsulesGalderma International
- IcelandOraceaGalderma Nordic AB*
- NorwayOraceaGalderma Nordic AB
- BelgiumEfracea 40 mgGalderma Benelux
- SwedenOracea 40 mg Kapsel med modifierad frisättning, hårdGalderma Nordic AB
- SpainORACEA 40 mg CAPSULAS DURAS DE LIBERACION MODIFICADALaboratorios Galderma S.A.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Doxybene, Doxycyclin G.L
- Belgium · Doxycycline Eg, Doxycycline Sandoz
- Bulgaria · Вибрамицин, Доксициклин Tzf
- Cyprus · Doxat, Medomycin
- Czechia · Deoxymykoin, Doxybene
- Germany · Doxakne Tabs, Doxy
- Denmark · Doxycycline Macure, Oracea
- Estonia · Adoxtar, Doxy-M
- Spain · Dosil, Doxiciclina Normon
- Finland · Doximed, Doximycin
- France · Doxy, Doxycycline Arrow
- United Kingdom (Northern Ireland) · Doxycycline, Doxycycline Accord-Uk
- Greece · Oracea, Smilitene
- Croatia · Doksiciklin Belupo
- Hungary · Doxitidin, Doxycyclin Al
- Ireland · Doxycycline Activase Pharmaceuticals, Doxycycline Athlone Pharmaceuticals
- Iceland · Doxycyklin Eql Pharma, Doxylin
- Italy · Bassado, Doxynor
- Liechtenstein · Ligosan
- Lithuania · Adoxtar, Doxitin
- Luxembourg · Doxycycline Eg, Doxycycline Sf Ratiopharm
- Latvia · Doxitin, Doxy-M
- Malta · Doxat, Doxycycline Activase
- Norway · Doksycyklin Hexal, Doxycycline Macure
- Poland · Doxyclinum Tzf, Doxycycline
- Portugal · Actidox, Adoxtar
- Romania · Doxiciclină Arena, Doxiciclina Atb
- Sweden · Doxycycline Macure, Doxycyklin Eql Pharma
- Slovenia · Doksivibra
- Slovakia · Deoxymykoin, Doxyhexal
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/45c38403-8036-49ff-9b03-d472d8572a2b GET /v1/drugs/45c38403-8036-49ff-9b03-d472d8572a2b?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Capsule met verlengde afgifte, hard",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h33759_smpc.pdf",
"strength": null,
"atc_label": "Doxycycline",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg33759",
"excipients": [
"ALLURAROOD AC ALUMINIUM LAK (E 129)",
"BRILJANTBLAUW FCF ALUMINIUMLAK (E133)",
"CHINOLINEGEEL ALUMINIUMLAK (E 104)",
"COPOLYMEER VAN ETHYLACRYLAAT-METHACRYLZUUR (1:1)",
"GELATINE (E 441)",
"HYPROMELLOSE (E 464)",
"IJZEROXIDE GEEL (E 172)",
"IJZEROXIDE GEEL (E 172)",
"IJZEROXIDE ROOD (E 172)",
"IJZEROXIDE ROOD (E 172)",
"IJZEROXIDE ZWART (E 172)",
"IJZEROXIDE ZWART (E 172)",
"INDIGOKARMIJN ALUMINIUMLAK (E 132)",
"MACROGOL 400",
"MAÏSZETMEEL",
"POLYSORBAAT 80 (E 433)",
"PROPYLEENGLYCOL (E 1520)",
"SACCHAROSE",
"SCHELLAK (E 904)",
"SUIKERZETMEELBOLLETJES",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)",
"TITAANDIOXIDE (E 171)",
"TRIETHYLCITRAAT (E 1505)",
"ZWARTE INKT"
],
"substances": [
"DOXYCYCLINE 1-WATER"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h33759.pdf",
"authorised_at": "2009/02/16",
"procedure_number": "SE/H/1984/001",
"dispensing_status": "Uitsluitend recept",
"registration_number": "33759",
"additional_monitoring": "N"
}See everything about doxycycline.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.