Canada· CA-DIN-02327856
APO-HYDROCHLOROTHIAZIDE
A hydrochlorothiazide product containing hydrochlorothiazide, registered in Canada by APOTEX INC. The same ATC class is registered in 16 of our 19 countries.
Checked against Health Canada Drug Product Database (Canada) on
Informational only — not a medical device.
Where it is registered
Hydrochlorothiazide is registered in 16 of 19 countries.
Countries holding a registration under ATC C03AA03 (hydrochlorothiazide), each read from that country’s own register.
- This record: Canada, from Health Canada Drug Product Database (Canada)
- 9 of them publish a price we can compare per daily dose
Hydrochlorothiazide · ATC C03AA03
16 / 19 countries
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of hydrochlorothiazide costs, country by country.
Normalised to the WHO defined daily dose (25 mg), the median price runs from $0.048 in France to $0.21 in Switzerland — a ×4.4 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Hydrochlorothiazide · price per daily dose (25 mg)
USD · FX 28 Sept 2026
- CH Switzerland$0.21
- IT Italy$0.075
- FR France$0.048
The record
At a glance
Health Canada Drug Product Database (Canada)- Active substance
- HYDROCHLOROTHIAZIDE
- Manufacturer
- APOTEX INC
- Country
- Canada (CA)
- ATC code
- C03AA03
- ATC class
- Hydrochlorothiazide
- Defined daily dose
- 25 mg, O
- Reimbursed
- Not published by this register
- Source register
- Health Canada Drug Product Database (Canada)
- Last checked
- October 1, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
490 interactions on record for hydrochlorothiazide.
Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Hydrochlorothiazide · interactions on record
490 records
- 4 severe
- 208 moderate
- 21 minor
- 169 info
Most severe, free to view
- CisaprideA03FA02severe
- DolasetronA04AA04severe
- Aminolevulinic acidL01XD04severe
- Arsenic trioxideL01XX27severe
88 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Hydrochlorothiazide in 14 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesHydrochlorothiazideNorthwind Health Company, LLC
- PolandHydrochlorothiazide AurovitasAurovitas Pharma Polska Sp. z o.o.
- SwedenHydrochlorothiazide Bluefish 12,5 mg TablettBluefish Pharmaceuticals AB
- IcelandHydromedEQL Pharma AB
- NorwayHydromedEQL Pharma AB
- SpainHIDROCLOROTIAZIDA CINFA 12,5 MG COMPRIMIDOSLaboratorios Cinfa S.A.
- FranceHYDROCHLOROTHIAZIDE ARROW 12,5 mg, comprimé sécableARROW GENERIQUES
- United KingdomHydrochlorothiazide 12.5mg tabletsSpecial Order
Authorised across Europe · EMA
The same active substance is authorised in 24 EEA countries. Names it is sold under:
- Austria · Hct G.L.
- Bulgaria · Hypodehydra, Дехидразид
- Cyprus · Didralin, Hydrochlorothiazide Remedica
- Czechia · Hydrochlorothiazid Léčiva
- Germany · Hct 089pharm, Hct 1 A Pharma
- Denmark · Hydrochlorothiazide Orifarm, Hydromed
- Estonia · Hypothiazid
- Spain · Drine, Esidrex
- Finland · Hydrex, Hydrex Semi
- France · Esidrex, Hydrochlorothiazide Arrow
- United Kingdom (Northern Ireland) · Hydrochlorothiazide Aspire Pharma
- Greece · Diuren, Losazide
- Hungary · Hypothiazid
- Iceland · Hydromed
- Italy · Esidrex, Idroclorotiazide Aurobindo
- Lithuania · Hypothiazid
- Latvia · Hypothiazid
- Netherlands · Hydrochloorthiazide 1a Pharma, Hydrochloorthiazide Aurobindo
- Norway · Esidrex, Hydrochlorothiazide Orifarm
- Poland · Hydrochlorothiazide Aurovitas, Hydrochlorothiazidum Polpharma
- Portugal · Hidroclorotiazida Bluefish, Hidroclorotiazida Generis
- Romania · Nefrix
- Sweden · Esidrex, Hydrochlorothiazide Bluefish
- Slovakia · Hydrochlorothiazid Léčiva
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/3bb89fdc-c580-4709-9f21-2b739e345a32 GET /v1/drugs/3bb89fdc-c580-4709-9f21-2b739e345a32?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"din": "02327856",
"form": "TABLET",
"class": "Human",
"routes": [
"ORAL"
],
"source": "health_canada_dpd",
"status": "MARKETED",
"atc_raw": "C03AA03",
"schedule": [
"Prescription"
],
"drug_code": "81335",
"strengths": [
"12.5 MG"
],
"ahfs_class": null,
"substances": [
"HYDROCHLOROTHIAZIDE"
],
"product_categorization": null
}See everything about hydrochlorothiazide.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.