Mekinist

{
  "unii": {
    "unii": "BSB9VJ5TUT",
    "rxcui": "1425098",
    "inchikey": "OQUFJVRYDFIQBW-UHFFFAOYSA-N",
    "display_name": "TRAMETINIB DIMETHYL SULFOXIDE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "spl_meta": {
    "0002ad27-779d-42ab-83b5-bc65453412a1": {
      "match": "brand_token",
      "title": "MEKINIST (TRAMETINIB) TABLET, FILM COATED MEKINIST (TRAMETINIB) POWDER, FOR SOLUTION [NOVARTIS PHARMACEUTICALS CORPORATION]",
      "spl_version": "35",
      "published_date": "2026-05-20"
    }
  },
  "productid": "0078-1105_235e3bc1-099b-4587-9d72-b02fcc3387d1",
  "productndc": "0078-1105",
  "dosage_form": "TABLET, FILM COATED",
  "orange_book": {
    "appl_no": "204114",
    "products": [
      {
        "rs": false,
        "rld": true,
        "te_code": null,
        "strength": "EQ 0.5MG",
        "product_no": "001",
        "approval_date": "May 29, 2013"
      },
      {
        "rs": false,
        "rld": true,
        "te_code": null,
        "strength": "EQ 1MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**",
        "product_no": "002",
        "approval_date": "May 29, 2013"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "EQ 2MG",
        "product_no": "003",
        "approval_date": "May 29, 2013"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "TRAMETINIB DIMETHYL SULFOXIDE",
  "proprietary_name": "Mekinist",
  "active_ingred_unit": "mg/1",
  "application_number": "NDA204114",
  "marketing_category": "NDA",
  "nonproprietary_name": "trametinib",
  "start_marketing_date": "20160317",
  "active_numerator_strength": ".5"
}