Spain· ES:12680
ASPIRINA PLUS 500 mg/ 50 mg COMPRIMIDOS
A medicinal product containing ácido acetilsalicílico + cafeína, registered in Spain by Bayer Hispania S.L..
Checked against AEMPS CIMA (Spain) on
Informational only — not a medical device.
The record
At a glance
AEMPS CIMA (Spain)- Active substance
- ácido acetilsalicílico + cafeína
- Manufacturer
- Bayer Hispania S.L.
- Country
- Spain (ES)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- AEMPS CIMA (Spain)
- Last checked
- September 12, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Ácido acetilsalicílico + cafeína in 11 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesAcetaminophen 250 mg Aspirin 250 mg Caffeine 65 mgHealth Pharma USA LLC
- SwedenBamyl koffein 500 mg/50 mg BrustablettCooper Consumer Health B.V.
- PolandCoffepirine Tabletki od bólu głowySopharma Warszawa Sp. z o.o.
- GermanyAspirin CoffeinBayer Vital Gmbh
- United KingdomAnadin Original tabletsHaleon UK Trading Ltd
- IcelandTreoCooper Consumer Health B.V.
- SwitzerlandContra-Schmerz plus, compriméVerfora SA
- IrelandAnadin Analgesic Film-coated Tablets Aspirin 325mg Caffeine 15mgHaleon Ireland Limited
Authorised across Europe · EMA
The same active substance is authorised in 15 EEA countries. Names it is sold under:
- Austria · Acedol
- Belgium · Aspirine Cafeine
- Czechia · Acylcoffin
- Germany · Aspirin Coffein, Doppel Spalt Compact
- Denmark · Treo, Treo Citrus
- Finland · Treo
- France · Aspro Cafeine
- United Kingdom (Northern Ireland) · Anadin Original, Beechams
- Hungary · Aspicont
- Ireland · Anadin Analgesic, Anadin Maximum Strength
- Iceland · Treo, Treo Citrus
- Luxembourg · Aspirine Cafeine
- Poland · Coffepirine Tabletki Od Bólu Głowy, Dampiryna
- Portugal · Melhoral, Salicylcafeina
- Sweden · Bamyl Koffein, Fyro
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of AEMPS CIMA (Spain). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/386d1c31-e49e-4487-8523-c5599ac7a797 GET /v1/drugs/386d1c31-e49e-4487-8523-c5599ac7a797?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cpresc": "Sin Receta",
"estado": "{\"aut\":-639108000000}",
"nregistro": "12680",
"substance": "ácido acetilsalicílico + cafeína"
}See everything about ácido acetilsalicílico + cafeína.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.