Canada· CA-DIN-02183005

LEUCOVORIN CALCIUM INJECTION USP

A calcium folinate product containing leucovorin (leucovorin calcium), registered in Canada by PFIZER CANADA ULC. The same ATC class is registered in 12 of our 19 countries.

ATC V03AF03

Checked against Health Canada Drug Product Database (Canada) on October 1, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about leucovorin (leucovorin calcium)Answers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Calcium folinate is registered in 12 of 19 countries.

Countries holding a registration under ATC V03AF03 (calcium folinate), each read from that country’s own register.

This record: Canada, from Health Canada Drug Product Database (Canada)
6 of them publish a price we can compare per daily dose

Search calcium folinate products by name

Calcium folinate · ATC V03AF03

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Ireland
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of calcium folinate costs, country by country.

Normalised to the WHO defined daily dose (60 mg), the median price runs from $0.25 in Czechia to $18.84 in Switzerland — a ×77 gap.

2 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Calcium folinate · price per daily dose (60 mg)

USD · FX 28 Sept 2026

CH Switzerland$18.84
CZ Czechia$0.25

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

Health Canada Drug Product Database (Canada)

Active substance: LEUCOVORIN (LEUCOVORIN CALCIUM)
Manufacturer: PFIZER CANADA ULC
Country: Canada (CA)
ATC code: V03AF03
ATC class: Calcium folinate
Defined daily dose: 60 mg, O
Reimbursed: Not published by this register
Source register: Health Canada Drug Product Database (Canada)
Last checked: October 1, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

352 interactions on record for calcium folinate.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check calcium folinate against other medicines How interaction checks work

Calcium folinate · interactions on record

352 records

4 severe
23 moderate
2 minor
323 info

Most severe, free to view

CeftriaxoneJ01DD04severe
TrimethoprimJ01EA01severe
FluorouracilL01BC02severe
CapecitabineL01BC06severe

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Calcium folinate in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All calcium folinate products

Authorised across Europe · EMA

The same active substance is authorised in 27 EEA countries. Names it is sold under:

Austria · Calciumfolinat Kabi, Calciumfolinat Sandoz
Belgium · Folikabi, Folinate Eg
Bulgaria · Bendafolin, Калциев Фолинат Алуфарма
Cyprus · Calcium Folinate Normon
Czechia · Calcium Folinate Kabi, Calcium Folinate Kalceks
Germany · Bendafolin, Calciumfolinat Hexal
Denmark · Calcium Folinate Kalceks, Calciumfolinat Fresenius Kabi
Spain · Folinato Cálcico Altan, Folinato Cálcico Hikma
Finland · Antrex, Calcium Folinate Kalceks
France · Folinate De Calcium Aguettant, Folinate De Calcium Altan
United Kingdom (Northern Ireland) · Calcium Folinate As Kalceks, Calcium Folinate Fresenius Kabi Deutschland
Greece · Buateron, Calcifolin
Croatia · Folinatna Kiselina Kalceks, Kalcijev Folinat Pliva
Hungary · Calcium Folinate Kabi, Calcium Folinate Kalceks
Ireland · Folinic Acid (As Calcium Folinate Hydrate) Pfizer Healthcare Ireland, Folinic Acid (As Calcium Folinate)
Italy · Citofolin
Lithuania · Calcium Folinate Sandoz, Folinic Acid Kalceks
Luxembourg · Folinate Eg, Folinic Acid Kalceks
Latvia · Calcium Folinate Kalceks, Calcium Folinate Sandoz
Malta · Fedolen, Medifolin
Netherlands · Folikabi, Folinezuur Kalceks
Norway · Calcium Folinate Kalceks
Poland · Calcium Folinate Kabi, Calcium Folinate Kalceks
Portugal · Folinato De Cálcio Hikma, Folinato De Cálcio Kabi
Romania · Folcasin, Folinat De Calciu Kabi
Sweden · Calcium Folinate Kalceks, Calciumfolinate Teva
Slovenia · Kalcijev Folinat Sandoz

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/30a1b418-8b34-4a89-a918-6004f60de831
GET /v1/drugs/30a1b418-8b34-4a89-a918-6004f60de831?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "din": "02183005",
  "form": "SOLUTION",
  "class": "Human",
  "routes": [
    "INTRAVENOUS",
    "INTRAMUSCULAR"
  ],
  "source": "health_canada_dpd",
  "status": "MARKETED",
  "atc_raw": "V03AF03",
  "schedule": [
    "Prescription"
  ],
  "drug_code": "44266",
  "strengths": [
    "10 MG"
  ],
  "ahfs_class": null,
  "substances": [
    "LEUCOVORIN (LEUCOVORIN CALCIUM)"
  ],
  "product_categorization": null
}

API reference MCP server Plans

See everything about calcium folinate.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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