United States· US:0280-1200_45265ccc-d985-a6ad-e063-6394a90a75b7
Aleve PM
A naproxen and diphenhydramine product containing diphenhydramine hydrochloride; naproxen sodium, registered in United States by Bayer HealthCare LLC..
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- DIPHENHYDRAMINE HYDROCHLORIDE; NAPROXEN SODIUM
- Manufacturer
- Bayer HealthCare LLC.
- Country
- United States (US)
- ATC code
- M01AE57
- ATC class
- Naproxen and diphenhydramine
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 18
- ndc11028012000580 TABLET, FILM COATED in 1 BOTTLE (0280-1200-05)
- ndc1102801200011 BOTTLE in 1 CARTON (0280-1200-01) / 120 TABLET, FILM COATED in 1 BOTTLE
- ndc1102801200022 TABLET, FILM COATED in 1 POUCH (0280-1200-02)
- ndc110280120003160 TABLET, FILM COATED in 1 BOTTLE (0280-1200-03)
- ndc1102801200041 BOTTLE in 1 CARTON (0280-1200-04) / 40 TABLET, FILM COATED in 1 BOTTLE
- ndc1102801200081 BOTTLE in 1 CARTON (0280-1200-08) / 250 TABLET, FILM COATED in 1 BOTTLE
- ndc1102801200201 BOTTLE in 1 CARTON (0280-1200-20) / 20 TABLET, FILM COATED in 1 BOTTLE
- ndc1102801200401 BOTTLE in 1 CARTON (0280-1200-40) / 40 TABLET, FILM COATED in 1 BOTTLE
- ndc1102801200801 BOTTLE in 1 CARTON (0280-1200-80) / 80 TABLET, FILM COATED in 1 BOTTLE
- ndc110280-1200-01
- ndc110280-1200-02
- ndc110280-1200-04
- ndc110280-1200-05
- ndc110280-1200-08
- ndc110280-1200-20
- ndc110280-1200-40
- ndc110280-1200-80
- ndc110280-1200-03
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Naproxen and diphenhydramine in 1 other country
What each register calls a product with the same active substance — salts and hydrates count as the same.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/2bdc06cd-04d7-468e-bcba-50dc931aa8f7 GET /v1/drugs/2bdc06cd-04d7-468e-bcba-50dc931aa8f7?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "ORAL",
"source": "ndc",
"strength": "25; 220",
"substance": "DIPHENHYDRAMINE HYDROCHLORIDE; NAPROXEN SODIUM",
"productndc": "0280-1200",
"dosage_form": "TABLET, FILM COATED",
"dea_schedule": null,
"strength_unit": "mg/1; mg/1",
"application_number": "NDA205352",
"marketing_category": "NDA"
}See everything about naproxen and diphenhydramine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.