Netherlands· NL-d43d8c461106

Codeïnefosfaat Costero 30 mg, tabletten

A codeine product containing codeinediwaterstoffosfaat 0,5-water, registered in Netherlands by Costero B.V.. The same ATC class is registered in 14 of our 19 countries.

ATC R05DA04

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about codeinediwaterstoffosfaat 0,5-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Codeine is registered in 14 of 19 countries.

Countries holding a registration under ATC R05DA04 (codeine), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
7 of them publish a price we can compare per daily dose

Search codeine products by name

Codeine · ATC R05DA04

14 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Ireland
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of codeine costs, country by country.

Normalised to the WHO defined daily dose (0.1 g), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Codeine · price per daily dose (0.1 g)

USD · FX 28 Sept 2026

CH Switzerland$1.98

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: CODEINEDIWATERSTOFFOSFAAT 0,5-WATER
Manufacturer: Costero B.V.
Country: Netherlands (NL)
ATC code: R05DA04
ATC class: Codeine
Defined daily dose: 0.1 g, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
127426

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

503 interactions on record for codeine.

Graded by severity as the source publishes them — 128 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check codeine against other medicines How interaction checks work

Codeine · interactions on record

503 records

128 severe
371 moderate
2 minor

Most severe, free to view

TriflupromazinA04AD06severe
AlvimopanA06AH02severe
ChlorphenesinD01AE07severe
ChlorphenesinG01AX21severe

2 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Codeine in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All codeine products

Authorised across Europe · EMA

The same active substance is authorised in 15 EEA countries. Names it is sold under:

Belgium · Bronchodine, Codeïne Met Eucalyptolsmaak Conforma
Czechia · Alyostal Prick, Codein Slovakofarma
Germany · Bronchi, Codeintropfen-Ct
Denmark · Kodein, Kodein Extractumpharma
Spain · Codeisan, Toseina
France · Paderyl
United Kingdom (Northern Ireland) · Codeine Linctus Bell’s Healthcare, Codeine Phosphate
Hungary · Codinep
Ireland · Codant, Codeine Phosphate Hemihydrate Extractum Pharma
Luxembourg · Toularynx
Malta · Codeine Phosphate, Galcodine Linctus care Sugar Free
Portugal · Toseína
Romania · Codeină Fosfat Lph Labormed, Codeină Fosfat Mcc
Sweden · Kodein, Kodein Extractumpharma
Slovakia · Alyostal Prick, Codein Slovakofarma

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/2b5709a6-a283-41ee-ab22-ba70a410ec56
GET /v1/drugs/2b5709a6-a283-41ee-ab22-ba70a410ec56?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h127426_smpc.pdf",
  "strength": null,
  "atc_label": "Codeine",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg127426",
  "excipients": [
    "AARDAPPELZETMEEL",
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "LACTOSE 1-WATER",
    "MAGNESIUMSTEARAAT (E 470b)",
    "SILICIUMDIOXIDE (E 551)",
    "TALK (E 553b)"
  ],
  "substances": [
    "CODEINEDIWATERSTOFFOSFAAT 0,5-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h127426.pdf",
  "authorised_at": "2022/10/03",
  "procedure_number": "NL/H/5297/004",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "127426",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about codeine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console