Netherlands· NL-bd1ef80c8b6e
Rapamune 1 mg/ml drank
A sirolimus product containing sirolimus, registered in Netherlands by Pfizer Europe MA EEIG. The same ATC class is registered in 13 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Sirolimus is registered in 13 of 19 countries.
Countries holding a registration under ATC L04AH01 (sirolimus), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 8 of them publish a price we can compare per daily dose
Sirolimus · ATC L04AH01
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of sirolimus costs, country by country.
Normalised to the WHO defined daily dose (3 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Sirolimus · price per daily dose (3 mg)
USD · FX 28 Sept 2026
- CH Switzerland$18.00
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- SIROLIMUS
- Manufacturer
- Pfizer Europe MA EEIG
- Country
- Netherlands (NL)
- ATC code
- L04AH01
- ATC class
- Sirolimus
- Defined daily dose
- 3 mg, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_idEU/1/01/171
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
737 interactions on record for sirolimus.
Graded by severity as the source publishes them — 162 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Sirolimus · interactions on record
737 records
- 162 severe
- 441 moderate
- 8 minor
- 126 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- NeomycinA07AA01severe
- StreptomycinA07AA04severe
- Polymyxin BA07AA05severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Sirolimus in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatessirolimusBryant Ranch Prepack
- CzechiaRAPAMUNEPfizer Europe MA EEIG, Bruxelles
- SpainRAPAMUNE 1 mg/ml SOLUCION ORALPfizer Europe Ma Eeig
- FinlandRapamunePfizer Europe MA EEIG
- FranceRAPAMUNE 1 mg/ml, solution buvablePFIZER EUROPE MA EEIG (BELGIQUE)
- BelgiumRapamune 1 mg/mlPfizer Europe MA
- IcelandRapamunePfizer Europe MA EEIG*
- NorwayRapamunePfizer Europe MA EEIG (1)
Authorised across Europe · EMA
The same active substance is authorised in 4 EEA countries. Names it is sold under:
- Germany · Sirolimus Panacea Biotec
- Iceland · Hyftor, Rapamune
- Liechtenstein · Hyftor, Rapamune
- Norway · Hyftor, Rapamune
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/2982d58e-1cdc-4ae6-b193-67de2d5aae39 GET /v1/drugs/2982d58e-1cdc-4ae6-b193-67de2d5aae39?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Drank",
"route": "Oraal gebruik",
"soort": null,
"source": "cbg_meb",
"smpc_url": "https://www.ema.europa.eu/en/documents/product-information/rapamune-epar-product-information_nl.pdf",
"strength": null,
"atc_label": "Sirolimus",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp70689",
"excipients": [
"ASCORBYLPALMITAAT (E 304)",
"ETHANOL",
"FOSFATIDYLCHOLINE, SOYA",
"MONO- EN DIGLYCERIDEN VAN VETZUREN (E 471)",
"POLYSORBAAT 80 (E 433)",
"PROPYLEENGLYCOL (E 1520)",
"SOJAVETZUREN",
"STIKSTOF (HEAD SPACE) (E 941)"
],
"substances": [
"SIROLIMUS"
],
"leaflet_url": null,
"authorised_at": "2001/05/17",
"procedure_number": "EMEA/H/C/000273",
"dispensing_status": "Uitsluitend recept",
"registration_number": "EU/1/01/171",
"additional_monitoring": "N"
}See everything about sirolimus.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.