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Netherlands· NL-bd1ef80c8b6e

Rapamune 1 mg/ml drank

A sirolimus product containing sirolimus, registered in Netherlands by Pfizer Europe MA EEIG. The same ATC class is registered in 13 of our 19 countries.

ATC L04AH01

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedRapamune 1 mg/ml drankATCL04AH01REGISTER NO.NL-bd1ef80c8b6ePACKS LISTED1CHECKEDSeptember 29, 2026

Where it is registered

Sirolimus is registered in 13 of 19 countries.

Countries holding a registration under ATC L04AH01 (sirolimus), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 8 of them publish a price we can compare per daily dose

Sirolimus · ATC L04AH01

13 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Germany
  • Icelandprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of sirolimus costs, country by country.

Normalised to the WHO defined daily dose (3 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Sirolimus · price per daily dose (3 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$18.00
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)
Active substance
SIROLIMUS
Manufacturer
Pfizer Europe MA EEIG
Country
Netherlands (NL)
ATC code
L04AH01
ATC class
Sirolimus
Defined daily dose
3 mg, O
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    EU/1/01/171

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

737 interactions on record for sirolimus.

Graded by severity as the source publishes them — 162 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Sirolimus · interactions on record

737 records

  • 162 severe
  • 441 moderate
  • 8 minor
  • 126 info

Most severe, free to view

  • ClotrimazoleA01AB18severe
  • NeomycinA07AA01severe
  • StreptomycinA07AA04severe
  • Polymyxin BA07AA05severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Sirolimus in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All sirolimus products

Authorised across Europe · EMA

The same active substance is authorised in 4 EEA countries. Names it is sold under:

  • Germany · Sirolimus Panacea Biotec
  • Iceland · Hyftor, Rapamune
  • Liechtenstein · Hyftor, Rapamune
  • Norway · Hyftor, Rapamune

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/2982d58e-1cdc-4ae6-b193-67de2d5aae39
GET /v1/drugs/2982d58e-1cdc-4ae6-b193-67de2d5aae39?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Drank",
  "route": "Oraal gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/rapamune-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Sirolimus",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp70689",
  "excipients": [
    "ASCORBYLPALMITAAT (E 304)",
    "ETHANOL",
    "FOSFATIDYLCHOLINE, SOYA",
    "MONO- EN DIGLYCERIDEN VAN VETZUREN (E 471)",
    "POLYSORBAAT 80 (E 433)",
    "PROPYLEENGLYCOL (E 1520)",
    "SOJAVETZUREN",
    "STIKSTOF (HEAD SPACE) (E 941)"
  ],
  "substances": [
    "SIROLIMUS"
  ],
  "leaflet_url": null,
  "authorised_at": "2001/05/17",
  "procedure_number": "EMEA/H/C/000273",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/01/171",
  "additional_monitoring": "N"
}

See everything about sirolimus.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.