Finland· FI-REL-REL60735
Advagraf
A tacrolimus product containing tacrolimus monohydrate, registered in Finland by Orifarm Oy. The same ATC class is registered in 16 of our 19 countries.
Checked against Fimea (Finland) on
Informational only — not a medical device.
Where it is registered
Tacrolimus is registered in 16 of 19 countries.
Countries holding a registration under ATC L04AD02 (tacrolimus), each read from that country’s own register.
- This record: Finland, from Fimea (Finland)
- 9 of them publish a price we can compare per daily dose
Tacrolimus · ATC L04AD02
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of tacrolimus costs, country by country.
Normalised to the WHO defined daily dose (5 mg), the median price runs from $0.77 in United States to $16.77 in Switzerland — a ×22 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Tacrolimus · price per daily dose (5 mg)
USD · FX 28 Sept 2026
- CH Switzerland$16.77
- IT Italy$8.99
- US United States$0.77 (acquisition cost)
The record
At a glance
Fimea (Finland)- Active substance
- Tacrolimus monohydrate
- Manufacturer
- Orifarm Oy
- Country
- Finland (FI)
- ATC code
- L04AD02
- ATC class
- Tacrolimus
- Defined daily dose
- 5 mg, O
- Reimbursed
- Not published by this register
- Source register
- Fimea (Finland)
- Last checked
- September 27, 2026
Packs & prices · 1
1 priced- fi_myyntilupa05712150EUR 59.28
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
1075 interactions on record for tacrolimus.
Graded by severity as the source publishes them — 238 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Tacrolimus · interactions on record
1075 records
- 238 severe
- 543 moderate
- 18 minor
- 217 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- OmeprazoleA02BC01severe
- LansoprazoleA02BC03severe
- EsomeprazoleA02BC05severe
59 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Tacrolimus in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaADVAGRAFAstellas Pharma Europe B.V., Leiden
- SpainADVAGRAF 0,5 MG CAPSULAS DURAS DE LIBERACION PROLONGADAAstellas Pharma Europe B.V.
- SwedenAdvagraf 0,5 mg Depotkapsel, hårdAstellas Pharma Europe BV
- NetherlandsAdvagraf 0,5 mg, capsules met verlengde afgifte, hardAstellas Pharma GmbH
- PolandAdvagrafAstellas Pharma Europe B.V.
- BelgiumAdvagraf 0.5 mgAstellas Pharma Europe
- United KingdomAdvagraf 0.5mg modified-release capsulesMawdsley-Brooks & Company Ltd
- IrelandAdvagraf 0.5 mg prolonged-release hard capsulesAstellas Pharma Europe BV
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Adport, Dailiport
- Belgium · Adoport, Dailiport
- Bulgaria · Програф
- Cyprus · Prograf, Tacrolimus Accord
- Czechia · Dailiport, Gecrol
- Germany · Crilomus, Dailiport
- Denmark · Adport, Dailiport
- Estonia · Dailiport, Lebsanan
- Spain · Adoport, Cellmune
- France · Adoport, Conferoport
- United Kingdom (Northern Ireland) · Adoport, Ascezo
- Greece · Atodrit-Dermo, Eczatope Derm
- Croatia · Atezyrix, Dermitopic
- Hungary · Prograf, Tacrolimus Stada
- Ireland · Prograf, Tacrolimus Accord
- Iceland · Advagraf, Dailiport
- Italy · Adoport, Carelimus
- Liechtenstein · Advagraf, Envarsus
- Lithuania · Dailiport, Lebsanan
- Luxembourg · Prograft, Sumilor
- Latvia · Dailiport, Lebsanan
- Malta · Prograf
- Netherlands · Adport, Conferoport
- Norway · Adport, Advagraf
- Poland · Cidimus, Dailiport
- Portugal · Adoport, Dermitopic
- Romania · Prograf, Tacrolimus Sandoz
- Sweden · Adport, Adport,
- Slovenia · Adoport, Dailiport
- Slovakia · Atezyrix, Dailiport
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Fimea (Finland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/28fdb471-eafb-4805-92da-836d80a5e9c3 GET /v1/drugs/28fdb471-eafb-4805-92da-836d80a5e9c3?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"ddd": "5",
"form": "depotkapseli, kova",
"route": "Suun kautta",
"ddd_unit": "mg",
"strength": "0.5 mg",
"atc_label": "takrolimuusi",
"ma_number": null,
"auth_status": "Myyntilupa myönnetty",
"eu_ma_number": "EU/1/07/387/002",
"fimea_rel_id": "REL60735",
"authorised_at": "2022-10-05"
}See everything about tacrolimus.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.