Netherlands· NL-60c7c2c7eaeb

Melfalan Hikma 50 mg, poeder en oplosmiddel voor oplossing voor injectie/infusie

A melphalan product containing melfalanhydrochloride + povidon k 12 (e 1201), registered in Netherlands by Hikma Farmaceutica (Portugal), S.A.. The same ATC class is registered in 17 of our 19 countries.

ATC L01AA03

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about melfalanhydrochloride + povidon k 12 (e 1201)Answers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Melphalan is registered in 17 of 19 countries.

Countries holding a registration under ATC L01AA03 (melphalan), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
10 of them publish a price we can compare per daily dose

Search melphalan products by name

Melphalan · ATC L01AA03

17 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of melphalan costs, country by country.

Normalised to the WHO defined daily dose (2 mg), the median price runs from $0.79 in Italy to $3.83 in Switzerland — a ×4.8 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Melphalan · price per daily dose (2 mg)

USD · FX 28 Sept 2026

CH Switzerland$3.83
FR France$0.89
IT Italy$0.79

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: MELFALANHYDROCHLORIDE + POVIDON K 12 (E 1201)
Manufacturer: Hikma Farmaceutica (Portugal), S.A.
Country: Netherlands (NL)
ATC code: L01AA03
ATC class: Melphalan
Defined daily dose: 2 mg, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
126892

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

242 interactions on record for melphalan.

Graded by severity as the source publishes them — 32 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check melphalan against other medicines How interaction checks work

Melphalan · interactions on record

242 records

32 severe
100 moderate
25 minor
85 info

Most severe, free to view

Nalidixic acidJ01MB02severe
ThiotepaL01AC01severe
CladribineL01BB04severe
Talimogene laherparepvecL01XL02severe

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same class

Other records under L01AA03

Melphalan, as other registers publish it.

All melphalan products

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/1bc557c5-61b0-48df-8357-978dafaaba9c
GET /v1/drugs/1bc557c5-61b0-48df-8357-978dafaaba9c?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Poeder en oplosmiddel voor oplossing voor injectie, Poeder en oplosmiddel voor oplossing voor infusie",
  "route": "Intraveneus gebruik, Intra-arterieel gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h126892_smpc.pdf",
  "strength": null,
  "atc_label": "Melphalan",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg126892",
  "excipients": [
    "ETHANOL",
    "PROPYLEENGLYCOL (E 1520)",
    "TRINATRIUMCITRAAT 2-WATER (E 331)",
    "WATER VOOR INJECTIE",
    "ZOUTZUUR (E 507)"
  ],
  "substances": [
    "MELFALANHYDROCHLORIDE",
    "POVIDON K 12 (E 1201)"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h126892.pdf",
  "authorised_at": "2023/10/10",
  "procedure_number": "AT/H/1132/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "126892",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about melphalan.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console