Canada· CA-DIN-00285455

ALDACTONE 100 MG

A spironolactone product containing spironolactone, registered in Canada by PFIZER CANADA ULC. The same ATC class is registered in 18 of our 19 countries.

ATC C03DA01

Checked against Health Canada Drug Product Database (Canada) on October 1, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about spironolactoneAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Spironolactone is registered in 18 of 19 countries.

Countries holding a registration under ATC C03DA01 (spironolactone), each read from that country’s own register.

This record: Canada, from Health Canada Drug Product Database (Canada)
10 of them publish a price we can compare per daily dose

Search spironolactone products by name

Spironolactone · ATC C03DA01

18 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of spironolactone costs, country by country.

Normalised to the WHO defined daily dose (37.5 mg), the median price runs from $0.064 in United States to $0.29 in Switzerland — a ×4.5 gap.

4 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Spironolactone · price per daily dose (37.5 mg)

USD · FX 28 Sept 2026

CH Switzerland$0.29
IT Italy$0.17
FR France$0.088
US United States$0.064 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

Health Canada Drug Product Database (Canada)

Active substance: SPIRONOLACTONE
Manufacturer: PFIZER CANADA ULC
Country: Canada (CA)
ATC code: C03DA01
ATC class: Spironolactone
Defined daily dose: 37.5 mg, O
Reimbursed: Not published by this register
Source register: Health Canada Drug Product Database (Canada)
Last checked: October 1, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

454 interactions on record for spironolactone.

Graded by severity as the source publishes them — 14 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check spironolactone against other medicines How interaction checks work

Spironolactone · interactions on record

454 records

14 severe
150 moderate
15 minor
191 info

Most severe, free to view

LoperamideA07DA03severe
Potassium chlorideA12BA01severe
Potassium citrateA12BA02severe
Potassium gluconateA12BA05severe

84 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Spironolactone in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All spironolactone products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

Austria · Aldactone, Spirobene
Belgium · Aldactone, Spironolactone Eg
Bulgaria · Спилактон, Спиронолактон Акорд
Cyprus · Spiro, Spirolon
Czechia · Spironolactone Medreg, Spironolactone Orion
Germany · Aldactone, Spirobeta
Denmark · Spirix, Spiron
Estonia · Spirix, Spironolactone Accord
Spain · Aldactone, Espironolactona Accord
Finland · Spirix, Spironolactone Orion
France · Aldactone, Spironolactone Arrow
United Kingdom (Northern Ireland) · Aldactone, Spironolactone Accord Healthcare
Greece · Aldactone
Croatia · Aldactone
Hungary · Spiron, Spironolactone Orion
Ireland · Aldactone, Spironolactone Accord Healthcare Ireland
Iceland · Spirix, Spiron
Italy · Aldactone, Spirolang
Lithuania · Spirix, Spironolactone Accord
Luxembourg · Aldactone, Spironolacton Ratiopharm
Latvia · Spirix, Spironolactone Accord
Malta · Aldactone, Spirolon
Netherlands · Spironolacton Accord, Spironolacton Genrx
Norway · Spirix, Spironolactone Orion
Poland · Finospir, Spironol
Portugal · Aldactone, Espironolactona Alter
Romania · Alspiron, Spironolactonă Arena
Sweden · Spironolactone Accord, Spironolactone Orion
Slovenia · Aldactone, Spironolakton Orion
Slovakia · Medospir, Spironolactone Accord

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/1992a3da-8418-48d9-a2d8-cdfdd7317cb6
GET /v1/drugs/1992a3da-8418-48d9-a2d8-cdfdd7317cb6?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "din": "00285455",
  "form": "TABLET",
  "class": "Human",
  "routes": [
    "ORAL"
  ],
  "source": "health_canada_dpd",
  "status": "MARKETED",
  "atc_raw": "C03DA01",
  "schedule": [
    "Prescription"
  ],
  "drug_code": "2145",
  "strengths": [
    "100 MG"
  ],
  "ahfs_class": null,
  "substances": [
    "SPIRONOLACTONE"
  ],
  "product_categorization": null
}

API reference MCP server Plans

See everything about spironolactone.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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