Ireland· IE-PA-EU/1/01/171/007
Rapamune 1 mg Coated tablet
A sirolimus product containing sirolimus, registered in Ireland by Pfizer Europe MA EEIG.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
The record
At a glance
HPRA (Ireland)- Active substance
- Sirolimus
- Manufacturer
- Pfizer Europe MA EEIG
- Country
- Ireland (IE)
- ATC code
- L04AA10
- ATC class
- Sirolimus
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberEU/1/01/171/007
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
740 interactions on record for sirolimus.
Graded by severity as the source publishes them — 162 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Sirolimus · interactions on record
740 records
- 162 severe
- 441 moderate
- 8 minor
- 126 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- NeomycinA07AA01severe
- StreptomycinA07AA04severe
- Polymyxin BA07AA05severe
3 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Sirolimus in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaRAPAMUNEPfizer Europe MA EEIG, Bruxelles
- BelgiumRapamune 1 mgPfizer Europe MA
- SpainRAPAMUNE 1 mg COMPRIMIDOS RECUBIERTOSPfizer Europe Ma Eeig
- FinlandRapamunePfizer Europe MA EEIG
- FranceRAPAMUNE 1 mg, comprimé enrobéPFIZER EUROPE MA EEIG (BELGIQUE)
- United StatesFYARROAadi Bioscience, Inc.
- United KingdomHyftor 2mg/g gelPlusultra Pharma UK Ltd
- SwitzerlandRapamune 0.5 mg, überzogene TablettenPfizer AG
Authorised across Europe · EMA
The same active substance is authorised in 4 EEA countries. Names it is sold under:
- Germany · Sirolimus Panacea Biotec
- Iceland · Hyftor, Rapamune
- Liechtenstein · Hyftor, Rapamune
- Norway · Hyftor, Rapamune
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/1964018d-8103-44e6-af04-2f02df18c3db GET /v1/drugs/1964018d-8103-44e6-af04-2f02df18c3db?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Coated tablet",
"routes": [
"Oral use"
],
"source": "hpra",
"atc_all": [
"L04AA",
"L04AA10"
],
"strength": null,
"pa_number": "EU/1/01/171/007",
"substances": [
"Sirolimus"
],
"legal_basis": "New active substance (Article 8(3) of Directive No 2001/83/EC)",
"market_info": "Unknown",
"authorised_at": "12/04/2002",
"dispensing_status": "Product subject to prescription which may not be renewed (A)",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about sirolimus.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.