Poland· PL-100229662
Metex
A methotrexate product containing methotrexatum, registered in Poland by medac Gesellschaft fuer klinische Spezialpraeparate mbH. The same ATC class is registered in 15 of our 19 countries.
ATC L04AX03
Checked against URPL (Poland) on
Informational only — not a medical device.
Where it is registered
Methotrexate is registered in 15 of 19 countries.
Countries holding a registration under ATC L04AX03 (methotrexate), each read from that country’s own register.
- This record: Poland, from URPL (Poland)
- 9 of them publish a price we can compare per daily dose
Methotrexate · ATC L04AX03
15 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of methotrexate costs, country by country.
Normalised to the WHO defined daily dose (2.5 mg), the median price runs from $0.16 in United States to $5.98 in Switzerland — a ×38 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Methotrexate · price per daily dose (2.5 mg)
USD · FX 28 Sept 2026
- CH Switzerland$5.98
- IT Italy$0.20
- US United States$0.16 (acquisition cost)
The record
At a glance
URPL (Poland)- Active substance
- Methotrexatum
- Manufacturer
- medac Gesellschaft fuer klinische Spezialpraeparate mbH
- Country
- Poland (PL)
- ATC code
- L04AX03
- ATC class
- Methotrexate
- Defined daily dose
- 2.5 mg, O
- Reimbursed
- Not published by this register
- Source register
- URPL (Poland)
- Last checked
- September 27, 2026
Packs & prices · 50
13 priced- gtin05909991263447
- gtin05909991263454
- gtin05909991054472
- gtin0590999092812512 amp.-strz.po 0,6 mlPLN 954.1
- gtin059099907913234 amp.-strz.po 0,2 mlPLN 107.35
- gtin059099907913784 amp.-strz.po 0,3 mlPLN 156.3
- gtin059099907914534 amp.-strz.po 0,4 mlPLN 204.64
- gtin0590999079152112 amp.-strz.po 0,5 mlPLN 798.06
- gtin05909990922659
- gtin05909990922666
- gtin05909990922673
- gtin05909990922697
- gtin05909990922703
- gtin05909990922727
- gtin05909990822171
- gtin05909990822188
- gtin05909990822195
- gtin05909990822201
- gtin05909990922734
- gtin0590999092275812 amp.-strz.po 0,35 mlPLN 562.63
- gtin0590999092276512 amp.-strz.po 0,45 mlPLN 719.66
- gtin0590999092277212 amp.-strz.po 0,55 mlPLN 875.69
- gtin05909990922789
- gtin05909990922796
- gtin05909990922802
- gtin05909990922833
- gtin0590999079128612 amp.-strz.po 0,15 mlPLN 248.69
- gtin0590999079134712 amp.-strz.po 0,2 mlPLN 327.23
- gtin0590999079139212 amp.-strz.po 0,3 mlPLN 484.31
- gtin0590999079147712 amp.-strz.po 0,4 mlPLN 641.42
- gtin0590999092274112 amp.-strz.po 0,25 mlPLN 405.61
- gtin05909991054182
- gtin05909991054199
- gtin05909991054205
- gtin05909991054250
- gtin05909991054267
- gtin05909991054274
- gtin05909991054281
- gtin05909991054298
- gtin05909991054304
- gtin05909991054342
- gtin05909991054359
- gtin05909991054366
- gtin05909991054373
- gtin05909991054380
- gtin05909991054397
- gtin05909991054403
- gtin05909991054434
- gtin05909991054441
- gtin05909991054458
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
929 interactions on record for methotrexate.
Graded by severity as the source publishes them — 107 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Methotrexate · interactions on record
929 records
- 107 severe
- 466 moderate
- 17 minor
- 309 info
Most severe, free to view
- OmeprazoleA02BC01severe
- PantoprazoleA02BC02severe
- LansoprazoleA02BC03severe
- RabeprazoleA02BC04severe
30 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Methotrexate in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaINJEXATEACCORD HEALTHCARE POLSKA Sp. z o.o., Varšava
- SwitzerlandMethotrexat Accord 10 mg/0.2 ml, Injektionslösung im FertiginjektorAccord Healthcare AG
- SpainMETHOFILL 10 MG/ 0,20 ML SOLUCION INYECTABLE EN JERINGA PRECARGADA EFGAccord Healthcare S.L.U.
- BelgiumMethofill 50 mg/mlAccord Healthcare
- ItalyMETOTHER*ACCORD HEALTHCARE SLU
- SwedenInjexate 50 mg/ml Injektionsvätska, lösning i förfylld sprutaAccord Healthcare B.V.
- United KingdomEbetrex 10mg/1ml solution for injection pre-filled syringesSandoz Ltd
- NetherlandsBasitrin 10 mg=0,267 ml, oplossing voor injectie in een voorgevulde spuit 37,5 mg/mlBasic Pharma Manufacturing B.V.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Ebetrexat, Methofill
- Belgium · Basitrin, Emthexate
- Bulgaria · Ebetrexat, Инжексат
- Cyprus · Injexate, Methotrexate Accord
- Czechia · Foxiemo, Injexate
- Germany · Lantarel, Lantarel Fs
- Denmark · Ebetrex, Emthexate
- Estonia · Ebetrex, Metex
- Spain · Bertanel, Imeth
- Finland · Ebetrex, Injexate
- France · Imenor, Imeth
- United Kingdom (Northern Ireland) · Ebetrex, Injexate
- Greece · Methobion, Methotrexate Pfizer
- Croatia · Ebetrexat, Methofill
- Hungary · Ebetrexat, Methofill
- Ireland · Methofill, Methotrexate Abcur
- Iceland · Jylamvo, Methotrexat Ebewe
- Italy · Afslamet, Immutrex
- Liechtenstein · Jylamvo, Nordimet
- Lithuania · Ebetrexat, Metex
- Luxembourg · Emthexate, Emthexate Teva Pharma
- Latvia · Ebetrex, Metex
- Malta · Methotrexate Aspire Pharma (Malta)
- Netherlands · Basitrin, Ebetrex
- Norway · Ebetrex, Jylamvo
- Portugal · Fauldexato, Ledertrexato
- Romania · Methotrexat Ebewe, Metorthrit
- Sweden · Ebetrex, Injexate
- Slovenia · Methofill, Metoject
- Slovakia · Foxiemo, Injexate
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/14f68da9-c021-44f9-a843-574c0f5527d9 GET /v1/drugs/14f68da9-c021-44f9-a843-574c0f5527d9?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Roztwór do wstrzykiwań",
"source": "urpl",
"strength": "50 mg/ml",
"packaging": "05909991054182 ¦ Rp ¦ 1783\n5 amp.-strzyk. 0,15 ml\n05909991054199 ¦ Rp ¦ 2302\n5 amp.-strzyk. 0,2 ml\n05909991054205 ¦ Rp ¦ 3199\n5 amp.-strzyk. 0,25 ml\n05909991054250 ¦ Rp ¦ 4380\n5 amp.-strzyk. 0,3 ml\n05909991054267 ¦ Rp ¦ 4522\n5 amp.-strzyk. 0,35 ml\n05909991054274 ¦ Rp ¦ 4564\n5 amp.-strzyk. 0,4 ml\n05909991054281 ¦ Rp ¦ 4686\n5 amp.-strzyk. 0,45 ml\n05909991054298 ¦ Rp ¦ 5173\n5 amp.-strzyk. 0,5 ml\n05909991054304 ¦ Rp ¦ 5218\n5 amp.-strzyk. 0,55 ml\n05909991054342 ¦ Rp ¦ 6228\n10 amp.-strzyk. 0,15 ml\n05909991054359 ¦ Rp ¦ 6748\n10 amp.-strzyk. 0,2 ml\n05909991054366 ¦ Rp ¦ 10466\n10 amp.-strzyk. 0,25 ml\n05909991054373 ¦ Rp ¦ 10653\n10 amp.-strzyk. 0,3 ml\n05909991054380 ¦ Rp ¦ 10897\n10 amp.-strzyk. 0,35 ml\n05909991054397 ¦ Rp ¦ 11795\n10 amp.-strzyk. 0,4 ml\n05909991054403 ¦ Rp ¦ 12263\n10 amp.-strzyk. 0,45 ml\n05909991054434 ¦ Rp ¦ 12670\n10 amp.-strzyk. 0,5 ml\n05909991054441 ¦ Rp ¦ 12854\n10 amp.-strzyk. 0,55 ml\n05909991054458 ¦ Rp ¦ 12877\n11 amp.-strzyk. 0,15 ml\n05909991054465 ¦ Rp ¦ 12986\n11 amp.-strzyk. 0,2 ml\n05909991054472 ¦ Rp ¦ 13150\n11 amp.-strzyk. 0,25 ml\n05909991054489 ¦ Rp ¦ 13248\n11 amp.-strzyk. 0,3 ml\n05909991054496 ¦ Rp ¦ 13524\n11 amp.-strzyk. 0,35 ml\n05909991054502 ¦ Rp ¦ 13727\n11 amp.-strzyk. 0,4 ml\n05909991054526 ¦ Rp ¦ 14043\n11 amp.-strzyk. 0,45 ml\n05909991054533 ¦ Rp ¦ 14277\n11 amp.-strzyk. 0,5 ml\n05909991054540 ¦ Rp ¦ 14505\n11 amp.-strzyk. 0,55 ml\n05909990928088 ¦ Rp ¦ 16432\n1 amp.-strzyk. 0,6 ml\n05909990928095 ¦ Rp ¦ 16461\n4 amp.-strzyk. 0,6 ml\n05909990928101 ¦ Rp ¦ 16491\n6 amp.-strzyk. 0,6 ml\n05909990928125 ¦ Rp ¦ 16560\n12 amp.-strzyk. 0,6 ml\n05909990928132 ¦ Rp ¦ 16596\n24 amp.-strzyk. 0,6 ml\n05909990791262 ¦ Rp ¦ 59113\n4 amp.-strzyk. 0,15 ml\n05909990791255 ¦ Rp ¦ 59229\n1 amp.-strzyk. 0,15 ml\n05909990791279 ¦ Rp ¦ 59232\n6 amp.-strzyk. 0,15 ml\n05909990791286 ¦ Rp ¦ 59233\n12 amp.-strzyk. 0,15 ml\n05909990791293 ¦ Rp ¦ 59237\n24 amp.-strzyk. 0,15 ml\n05909990791309 ¦ Rp ¦ 59238\n1 amp.-strzyk. 0,2 ml\n05909990791323 ¦ Rp ¦ 59239\n4 amp.-strzyk. 0,2 ml\n05909990791330 ¦ Rp ¦ 59240\n6 amp.-strzyk. 0,2 ml\n05909990791347 ¦ Rp ¦ 59241\n12 amp.-strzyk. 0,2 ml\n05909990791354 ¦ Rp ¦ 59245\n24 amp.-strzyk. 0,2 ml\n05909990791361 ¦ Rp ¦ 59246\n1 amp.-strzyk. 0,3 ml\n05909990791378 ¦ Rp ¦ 59247\n4 amp.-strzyk. 0,3 ml\n05909990791385 ¦ Rp ¦ 59248\n6 amp.-strzyk. 0,3 ml\n05909990791392 ¦ Rp ¦ 59249\n12 amp.-strzyk. 0,3 ml\n05909990791408 ¦ Rp ¦ 59250\n24 amp.-strzyk. 0,3 ml\n05909990791446 ¦ Rp ¦ 59251\n1 amp.-strzyk. 0,4 ml\n05909990791453 ¦ Rp ¦ 59252\n4 amp.-strzyk. 0,4 ml\n05909990791460 ¦ Rp ¦ 59256\n6 amp.-strzyk. 0,4 ml\n05909990791477 ¦ Rp ¦ 59257\n12 amp.-strzyk. 0,4 ml\n05909990791484 ¦ Rp ¦ 59258\n24 amp.-strzyk. 0,4 ml\n05909990791491 ¦ Rp ¦ 59259\n1 amp.-strzyk. 0,5 ml\n05909990791507 ¦ Rp ¦ 59260\n4 amp.-strzyk. 0,5 ml\n05909990791514 ¦ Rp ¦ 59261\n6 amp.-strzyk. 0,5 ml\n05909990791521 ¦ Rp ¦ 59262\n12 amp.-strzyk. 0,5 ml\n05909990791538 ¦ Rp ¦ 59263\n24 amp.-strzyk. 0,5 ml\n05909990922642 ¦ Rp ¦ 60338\n4 amp.-strzyk. 0,25 ml\n05909990922659 ¦ Rp ¦ 60339\n4 amp.-strzyk. 0,35 ml\n05909990922666 ¦ Rp ¦ 60371\n4 amp.-strzyk. 0,45 ml\n05909990922673 ¦ Rp ¦ 60463\n4 amp.-strzyk. 0,55 ml\n05909990922697 ¦ Rp ¦ 60465\n6 amp.-strzyk. 0,25 ml\n05909990922703 ¦ Rp ¦ 60468\n6 amp.-strzyk. 0,35 ml\n05909990922727 ¦ Rp ¦ 62090\n6 amp.-strzyk. 0,45 ml\n05909990822171 ¦ Rp ¦ 62158\n1 amp.-strzyk. 0,25 ml\n05909990822188 ¦ Rp ¦ 62159\n1 amp.-strzyk. 0,55 ml\n05909990822195 ¦ Rp ¦ 62160\n1 amp.-strzyk. 0,35 ml\n05909990822201 ¦ Rp ¦ 62161\n1 amp.-strzyk. 0,45 ml\n05909990922734 ¦ Rp ¦ 62286\n6 amp.-strzyk. 0,55 ml\n05909990922741 ¦ Rp ¦ 62349\n12 amp.-strzyk. 0,25 ml\n05909990922758 ¦ Rp ¦ 63004\n12 amp.-strzyk. 0,35 ml\n05909990922765 ¦ Rp ¦ 63223\n12 amp.-strzyk. 0,45 ml\n05909990922772 ¦ Rp ¦ 63928\n12 amp.-strzyk. 0,55 ml\n05909990922789 ¦ Rp ¦ 63983\n24 amp.-strzyk. 0,25 ml\n05909990922796 ¦ Rp ¦ 64208\n24 amp.-strzyk. 0,35 ml\n05909990922802 ¦ Rp ¦ 64209\n24 amp.-strzyk. 0,45 ml\n05909990922833 ¦ Rp ¦ 64210\n24 amp.-strzyk. 0,55 ml\n05909991263430 ¦ Rp ¦ Skasowane ¦ 114331\n10 amp.-strzyk. 0,6 ml\n05909991263447 ¦ Rp ¦ Skasowane ¦ 114332\n11 amp.-strzyk. 0,6 ml\n05909991263454 ¦ Rp ¦ Skasowane ¦ 114333\n5 amp.-strzyk. 0,6 ml",
"substance": "Methotrexatum natricum 54.84 mg",
"common_name": "Methotrexatum",
"pl_product_id": "100229662",
"pozwolenie_nr": "16976",
"auth_procedure": "DCP",
"authorisation_validity": "Bezterminowe"
}See everything about methotrexate.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.