Poland· PL-100396242
Ayupil
A clozapine product containing clozapinum, registered in Poland by Synthon B.V.. The same ATC class is registered in 17 of our 19 countries.
Checked against URPL (Poland) on
Informational only — not a medical device.
Where it is registered
Clozapine is registered in 17 of 19 countries.
Countries holding a registration under ATC N05AH02 (clozapine), each read from that country’s own register.
- This record: Poland, from URPL (Poland)
- 10 of them publish a price we can compare per daily dose
Clozapine · ATC N05AH02
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of clozapine costs, country by country.
Normalised to the WHO defined daily dose (0.3 g), the median price runs from $1.63 in France to $2.78 in Switzerland — a ×1.7 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Clozapine · price per daily dose (0.3 g)
USD · FX 28 Sept 2026
- CH Switzerland$2.78
- IT Italy$2.38
- FR France$1.63
The record
At a glance
URPL (Poland)- Active substance
- Clozapinum
- Manufacturer
- Synthon B.V.
- Country
- Poland (PL)
- ATC code
- N05AH02
- ATC class
- Clozapine
- Defined daily dose
- 0.3 g, O
- Reimbursed
- Not published by this register
- Source register
- URPL (Poland)
- Last checked
- September 27, 2026
Packs & prices · 36
- gtin05909991410117
- gtin05909991410124
- gtin05909991410131
- gtin05909991410148
- gtin05909991410155
- gtin05909991410162
- gtin05909991410179
- gtin05909991410186
- gtin05909991410193
- gtin05909991410209
- gtin05909991410216
- gtin05909991410223
- gtin05909991410285
- gtin05909991410292
- gtin05909991410025
- gtin05909991410032
- gtin05909991410049
- gtin05909991410056
- gtin05909991410063
- gtin05909991410070
- gtin05909991410087
- gtin05909991410094
- gtin05909991410100
- gtin05909991410230
- gtin05909991410247
- gtin05909991410254
- gtin05909991410261
- gtin05909991410278
- gtin05909991410308
- gtin05909991410315
- gtin05909991410322
- gtin05909991410339
- gtin05909991410346
- gtin05909991410353
- gtin05909991410360
- gtin05909991410377
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
620 interactions on record for clozapine.
Graded by severity as the source publishes them — 306 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Clozapine · interactions on record
620 records
- 306 severe
- 197 moderate
- 4 minor
- 61 info
Most severe, free to view
- PapaverineA03AD01severe
- MetoclopramideA03FA01severe
- CisaprideA03FA02severe
- OndansetronA04AA01severe
52 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Clozapine in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClozapine 200mg orodispersible tablets sugar freeViatris UK Healthcare Ltd
- United StatesClozapineAurobindo Pharma Limited
- SpainNEMEA 200 MG COMPRIMIDOS BUCODISPERSABLESAdamed Laboratorios S.L.U.
- FinlandLeponexViatris Oy
- IrelandLeydex 200 mg Orodispersible TabletsLeyden Delta BV
- NetherlandsAyupine 100 mg, orodispergeerbare tablettenSynthon B.V.
- CzechiaCLOZAPIN DESITINDesitin Arzneimittel GmbH, Hamburg
- FranceCLOZAPINE ACCORD 100 mg, comprimé sécableACCORD HEALTHCARE FRANCE
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Clozapin Accord, Clozapin Ratiopharm
- Belgium · Clozapine Sandoz, Leponex
- Bulgaria · Ексклоза, Клозапин Акорд
- Cyprus · Clozapine Accord, Clozarem
- Czechia · Clozapin Desitin, Leponex
- Germany · Clozapin 1a-Pharma, Clozapin Abz
- Denmark · Clozapin Accord, Clozapin Hexal
- Estonia · Clozapine Accord, Leponex
- Spain · Clozabrain, Clozapina Aurovitas
- Finland · Clozapine Accord, Clozapine Stada
- France · Clozapine Accord, Clozapine Aristo
- United Kingdom (Northern Ireland) · Clozapine, Clozapine Viatris
- Greece · Leponex
- Croatia · Klozapin Accord, Klozapin Alpha-Medical
- Hungary · Clozapine Gerot, Clozapine Stada
- Ireland · Clozaril, Denzapine
- Iceland · Clozapin Medical, Clozapine Actavis
- Italy · Clozapina Accord, Clozapina Aurobindo
- Lithuania · Clozapine Accord, Leponex
- Luxembourg · Leponex
- Latvia · Clozapine Accord, Leponex
- Malta · Clozarem
- Netherlands · Ayupine, Clozapine Accord
- Norway · Clozapin Hexal, Clozapine Accord
- Portugal · Clozapina Aristo, Clozapina Aurovitas
- Romania · Leponex
- Sweden · Clozapine Accord, Clozapine Actavis
- Slovenia · Klozapin Accord, Leponex
- Slovakia · Clozapine Accord, Leponex
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/13d2fcef-c9bd-43c4-bd9a-13543b9a822d GET /v1/drugs/13d2fcef-c9bd-43c4-bd9a-13543b9a822d?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tabletki ulegające rozpadowi w jamie ustnej",
"source": "urpl",
"strength": "200 mg",
"packaging": "05909991410025 ¦ Rp ¦ 133461\n7 tabl. w blistrze perforowanym\n05909991410032 ¦ Rp ¦ 133462\n7 tabl. w blistrze\n05909991410049 ¦ Rp ¦ 133463\n10 tabl. w blistrze perforowanym\n05909991410056 ¦ Rp ¦ 133464\n10 tabl. w blistrze\n05909991410063 ¦ Rp ¦ 133465\n14 tabl. w blistrze perforowanym\n05909991410070 ¦ Rp ¦ 133466\n14 tabl. w blistrze\n05909991410087 ¦ Rp ¦ 133467\n20 tabl. w blistrze\n05909991410094 ¦ Rp ¦ 133468\n20 tabl. w blistrze perforowanym\n05909991410100 ¦ Rp ¦ 133469\n28 tabl. w blistrze\n05909991410117 ¦ Rp ¦ 133470\n28 tabl. w blistrze perforowanym\n05909991410124 ¦ Rp ¦ 133471\n30 tabl. w blistrze\n05909991410131 ¦ Rp ¦ 133472\n30 tabl. w blistrze perforowanym\n05909991410148 ¦ Rp ¦ 133473\n40 tabl. w blistrze perforowanym\n05909991410155 ¦ Rp ¦ 133474\n40 tabl. w blistrze\n05909991410162 ¦ Rp ¦ 133475\n50 tabl. w blistrze\n05909991410179 ¦ Rp ¦ 133476\n50 tabl. w blistrze perforowanym\n05909991410186 ¦ Rp ¦ 133477\n56 tabl. w blistrze\n05909991410193 ¦ Rp ¦ 133478\n56 tabl. w blistrze perforowanym\n05909991410209 ¦ Rp ¦ 133479\n60 tabl. w blistrze perforowanym\n05909991410216 ¦ Rp ¦ 133480\n60 tabl. w blistrze\n05909991410223 ¦ Rp ¦ 133481\n84 tabl. w blistrze perforowanym\n05909991410230 ¦ Rp ¦ 133482\n84 tabl. w blistrze\n05909991410247 ¦ Rp ¦ 133483\n90 tabl. w blistrze perforowanym\n05909991410254 ¦ Rp ¦ 133484\n90 tabl. w blistrze\n05909991410261 ¦ Rp ¦ 133485\n98 tabl. w blistrze perforowanym\n05909991410278 ¦ Rp ¦ 133486\n98 tabl. w blistrze\n05909991410285 ¦ Rp ¦ 133487\n100 tabl. w blistrze perforowanym\n05909991410292 ¦ Rp ¦ 133488\n100 tabl. w blistrze\n05909991410308 ¦ Rp ¦ 133489\n250 tabl. w blistrze\n05909991410315 ¦ Rp ¦ 133490\n250 tabl. w butelce\n05909991410322 ¦ Rp ¦ 133491\n250 tabl. w blistrze perforowanym\n05909991410339 ¦ Rp ¦ 133492\n275 tabl. w butelce\n05909991410346 ¦ Rp ¦ 133493\n300 tabl. w blistrze perforowanym\n05909991410353 ¦ Rp ¦ 133494\n300 tabl. w blistrze\n05909991410360 ¦ Rp ¦ 133495\n500 tabl. w blistrze\n05909991410377 ¦ Rp ¦ 133496\n500 tabl. w blistrze perforowanym",
"substance": "Clozapinum 200 mg",
"common_name": "Clozapinum",
"pl_product_id": "100396242",
"pozwolenie_nr": "25453",
"auth_procedure": "DCP",
"authorisation_validity": "2024-11-04"
}See everything about clozapine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.