Rasuvo

{
  "unii": {
    "unii": "3IG1E710ZN",
    "rxcui": "287734",
    "inchikey": "DASQOOZCTWOQPA-GXKRWWSZSA-L",
    "display_name": "METHOTREXATE SODIUM",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "SUBCUTANEOUS",
  "spl_meta": {
    "d0075461-0e7e-4967-9c9b-d6440e912c0e": {
      "match": "brand_token",
      "title": "RASUVO (METHOTREXATE) INJECTION, SOLUTION [MEDEXUS PHARMA INC.]",
      "spl_version": "10",
      "published_date": "2025-12-18"
    }
  },
  "productid": "59137-535_29d04017-dd64-4dea-a064-7b3b0805f423",
  "productndc": "59137-535",
  "dosage_form": "INJECTION, SOLUTION",
  "orange_book": {
    "appl_no": "205776",
    "products": [
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "7.5MG/0.15ML (7.5MG/0.15ML)",
        "product_no": "001",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "10MG/0.20ML (10MG/0.20ML)",
        "product_no": "002",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "12.5MG/0.25ML (12.5MG/0.25ML)",
        "product_no": "003",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "15MG/0.30ML (15MG/0.30ML)",
        "product_no": "004",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "17.5MG/0.35ML (17.5MG/0.35ML)",
        "product_no": "005",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "20MG/0.4ML (20MG/0.4ML)",
        "product_no": "006",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "22.5MG/0.45ML (22.5MG/0.45ML)",
        "product_no": "007",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "25MG/0.5ML (25MG/0.5ML)",
        "product_no": "008",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": false,
        "rld": true,
        "te_code": null,
        "strength": "27.5MG/0.55ML (27.5MG/0.55ML)",
        "product_no": "009",
        "approval_date": "Jul 10, 2014"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "30MG/0.6ML (30MG/0.6ML)",
        "product_no": "010",
        "approval_date": "Jul 10, 2014"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "METHOTREXATE SODIUM",
  "shortage_reason": "Methotrexate Sodium Injection",
  "shortage_status": "current",
  "proprietary_name": "Rasuvo",
  "active_ingred_unit": "mg/.45mL",
  "application_number": "NDA205776",
  "marketing_category": "NDA",
  "nonproprietary_name": "methotrexate",
  "start_marketing_date": "20140710",
  "active_numerator_strength": "22.5"
}