Ireland· IE-PA-PA2307/005/001
Pulmozyme 2500 U/ 2.5ml, nebuliser solution
A dornase alfa (desoxyribonuclease) product containing dornase alfa, registered in Ireland by Roche Products (Ireland) Limited. The same ATC class is registered in 11 of our 19 countries.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
Where it is registered
Dornase alfa (desoxyribonuclease) is registered in 11 of 19 countries.
Countries holding a registration under ATC R05CB13 (dornase alfa (desoxyribonuclease)), each read from that country’s own register.
- This record: Ireland, from HPRA (Ireland)
- 7 of them publish a price we can compare per daily dose
Dornase alfa (desoxyribonuclease) · ATC R05CB13
11 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
The record
At a glance
HPRA (Ireland)- Active substance
- Dornase alfa
- Manufacturer
- Roche Products (Ireland) Limited
- Country
- Ireland (IE)
- ATC code
- R05CB13
- ATC class
- Dornase alfa (desoxyribonuclease)
- Defined daily dose
- 2.5 mg, Inhal
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberPA2307/005/001
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
5 interactions on record for dornase alfa (desoxyribonuclease).
Graded by severity as the source publishes them — 5 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Dornase alfa (desoxyribonuclease) · interactions on record
5 records
- 5 moderate
Most severe, free to view
- Insulin (human)A10AB01moderate
- Insulin (human)A10AC01moderate
- Insulin (human)A10AD01moderate
- Insulin (human)A10AE01moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Dornase alfa (desoxyribonuclease) in 15 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwedenPulmozyme 1 mg/ml Lösning för nebulisatorMedartuum AB
- NetherlandsPulmozyme 2500 E/2,5 ml, verneveloplossingBModesto B.V.
- United KingdomPulmozyme 2.5mg nebuliser liquid 2.5ml ampoulesDowelhurst Ltd
- CzechiaPULMOZYMEROCHE s.r.o., Praha
- SpainPULMOZYME 2.500 U/2,5 ml SOLUCIÓN PARA INHALACIÓN POR NEBULIZADORRoche Farma S.A.
- FinlandPulmozymeRoche Oy
- IcelandPulmozymeRoche Pharmaceuticals A/S
- Japanドルナーゼ アルファ(遺伝子組換え)中外製薬
Authorised across Europe · EMA
The same active substance is authorised in 28 EEA countries. Names it is sold under:
- Austria · Pulmozyme
- Belgium · Pulmozyme
- Bulgaria · Пулмозим
- Cyprus · Pulmozyme
- Czechia · Pulmozyme
- Germany · Pulmozyme
- Denmark · Pulmozyme
- Estonia · Pulmozyme
- Spain · Pulmozyme
- Finland · Pulmozyme
- France · Pulmozyme
- United Kingdom (Northern Ireland) · Pulmozyme
- Greece · Pulmozyme
- Croatia · Pulmozyme Otopina Za Atomizator
- Hungary · Pulmozyme
- Iceland · Pulmozyme
- Italy · Pulmozyme
- Lithuania · Pulmozyme
- Luxembourg · Pulmozyme
- Latvia · Pulmozyme
- Netherlands · Pulmozyme Verneveloplossing
- Norway · Pulmozyme
- Poland · Pulmozyme
- Portugal · Pulmozyme
- Romania · Pulmozyme
- Sweden · Pulmozyme
- Slovenia · Pulmozyme
- Slovakia · Pulmozyme
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/0c429768-9012-4ca8-a6f9-571ea7bf4124 GET /v1/drugs/0c429768-9012-4ca8-a6f9-571ea7bf4124?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Nebuliser solution",
"routes": [
"Inhalation use"
],
"source": "hpra",
"atc_all": [
"R05CB",
"R05CB13"
],
"strength": null,
"pa_number": "PA2307/005/001",
"substances": [
"Dornase alfa"
],
"legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
"market_info": "Marketed",
"authorised_at": "14/03/1994",
"dispensing_status": "Product subject to prescription which may be renewed (B)",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about dornase alfa (desoxyribonuclease).
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.