United States· US:60687-422_1fa7387b-3149-96a2-e063-6394a90ad8aa

Amantadine

A amantadine product containing amantadine, registered in United States by American Health Packaging. The same ATC class is registered in 14 of our 19 countries.

In shortageATC N04BB01Orange BookUS label

Checked against FDA National Drug Code directory (United States) on September 12, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about amantadineAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Amantadine is registered in 14 of 19 countries.

Countries holding a registration under ATC N04BB01 (amantadine), each read from that country’s own register.

This record: United States, from FDA National Drug Code directory (United States)
7 of them publish a price we can compare per daily dose

Search amantadine products by name

Amantadine · ATC N04BB01

14 / 19 countries

Canada
Czechiaprice
Denmark
Finlandprice
Germany
Ireland
Japan
Netherlands
Norwayprice
Polandprice
Spainprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of amantadine costs, country by country.

Normalised to the WHO defined daily dose (0.2 g), the median price runs from $0.28 in United States to $0.65 in Switzerland — a ×2.3 gap.

United States: $0.28 per daily dose (median across products in the class)
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Amantadine · price per daily dose (0.2 g)

USD · FX 28 Sept 2026

CH Switzerland$0.65
ES Spain$0.54
US United States$0.28 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)

Active substance: Amantadine
Manufacturer: American Health Packaging
Country: United States (US)
ATC code: N04BB01
ATC class: Amantadine
Defined daily dose: 0.2 g, O
Reimbursed: Not published by this register
Source register: FDA National Drug Code directory (United States)
Last checked: September 12, 2026

Packs & prices · 1

ndc11
6068742201
100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-422-01) / 1 CAPSULE in 1 BLISTER PACK (60687-422-11)

Regulatory notes

UNII (FDA substance ID)

M6Q1EO9TD0

AMANTADINE HYDROCHLORIDE

RxCUI 282415

Orange Book

A208966

DailyMed SPL labels

1 version tracked

FDA shortage

Currently in shortage

Amantadine Hydrochloride Capsule

Interactions

118 interactions on record for amantadine.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check amantadine against other medicines How interaction checks work

Amantadine · interactions on record

118 records

4 severe
55 moderate
58 info

Most severe, free to view

BupropionN06AX12severe
BupropionN07BA02severe
IohexolV08AB02severe
IopamidolV08AB04severe

1 more interaction with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Amantadine in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All amantadine products

Authorised across Europe · EMA

The same active substance is authorised in 26 EEA countries. Names it is sold under:

Austria · Pk-Merz Schoeller, Pk-Merz-Schoeller
Bulgaria · Пк-Мерц
Czechia · Pk-Merz, Viregyt-K
Germany · Amantadin 1 A Pharma, Amantadin Neuraxpharm
Denmark · Amypha, Dinetrel
Estonia · Amantadin Ratiopharm
Spain · Amantadine Level
Finland · Amypha, Parkadin
France · Mantadix
United Kingdom (Northern Ireland) · Amantadine Hydrochloride Crescent Pharma, Amantadine Hydrochloride Dawa
Greece · Symmetrel
Croatia · Pk-Merz
Hungary · Pk-Merz, Viregyt
Ireland · Amantadine Hydrochloride Renata
Italy · Mantadan
Lithuania · Amantadin Ratiopharm, Pk-Merz
Luxembourg · Pk-Merz®, Pk-Merz® Infusion
Latvia · Neomidantan, Pk-Merz
Malta · Amantadine Hydrochloride Renata, Parkadina
Netherlands · Amantadine Hcl Renata, Amypha
Norway · Amypha, Dinetrel
Poland · Amantix, Viregyt-K
Portugal · Amantadina Renata, Amantadina Renata 100 Mg Cápsulas
Romania · Viregyt-K
Sweden · Amypha, Dinetrel
Slovakia · Pk-Merz, Viregyt-K

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/07aac127-487a-47f2-afae-9dc6a5a517d7
GET /v1/drugs/07aac127-487a-47f2-afae-9dc6a5a517d7?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unii": {
    "unii": "M6Q1EO9TD0",
    "rxcui": "282415",
    "inchikey": "WOLHOYHSEKDWQH-UHFFFAOYSA-N",
    "display_name": "AMANTADINE HYDROCHLORIDE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "livertox": {
    "summary": null,
    "livertox_id": null,
    "hepatotoxicity_score": 5
  },
  "spl_meta": {
    "da693bb0-0cc8-485d-89a7-c8cf28d440f3": {
      "match": "brand_token",
      "title": "AMANTADINE HYDROCHLORIDE CAPSULE [A-S MEDICATION SOLUTIONS]",
      "spl_version": "8",
      "published_date": "2026-05-20"
    }
  },
  "productid": "60687-422_1fa7387b-3149-96a2-e063-6394a90ad8aa",
  "productndc": "60687-422",
  "dosage_form": "CAPSULE",
  "orange_book": {
    "appl_no": "208966",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "100MG",
        "product_no": "001",
        "approval_date": "Jun 21, 2017"
      }
    ],
    "appl_type": "A"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "AMANTADINE HYDROCHLORIDE",
  "shortage_reason": "Amantadine Hydrochloride Capsule",
  "shortage_status": "current",
  "proprietary_name": "Amantadine",
  "active_ingred_unit": "mg/1",
  "application_number": "ANDA208966",
  "marketing_category": "ANDA",
  "nonproprietary_name": "Amantadine",
  "start_marketing_date": "20190501",
  "active_numerator_strength": "100"
}

API reference MCP server Plans

See everything about amantadine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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