France· FR:67140828
IPRAFEINE 400 mg/100 mg, comprimé pelliculé
A medicinal product containing caféine + ibuprofène, registered in France by OPELLA HEALTHCARE FRANCE.
Checked against Base de données publique des médicaments — BDPM (France) on
Informational only — not a medical device.
The record
At a glance
Base de données publique des médicaments — BDPM (France)- Active substance
- CAFÉINE + IBUPROFÈNE
- Manufacturer
- OPELLA HEALTHCARE FRANCE
- Country
- France (FR)
- ATC code
- —
- Reimbursed
- No
- Source register
- Base de données publique des médicaments — BDPM (France)
- Last checked
- September 12, 2026
Packs & prices · 1
- cip133400930074923plaquette(s) PVC PVDC aluminium de 12 comprimé(s)
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Caféine + ibuprofène in 5 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- GermanyIbuprofen/Coffein SanofiA. Nattermann & Cie. Gmbh
- SpainDOLALGIAL IBUPROFENO/CAFEINA 400 MG/100 MG COMPRIMIDOS RECUBIERTOS CON PELICULAOpella Healthcare Spain S.L.
- FinlandIbuxin CoffeinTeva B.V.
- IcelandÍbúfen ExtraTeva B.V.*
- PolandIBU-SPAOpella Healthcare Poland Sp. z o.o.
Authorised across Europe · EMA
The same active substance is authorised in 9 EEA countries. Names it is sold under:
- Austria · Thomaduo
- Germany · Ibuprofen/Coffein Sanofi, Thomapyrin Tension Duo
- Estonia · Ibuprofen/Caffeine Teva
- Finland · Ibuxin Coffein
- Greece · Buscofem Extra
- Hungary · Algoflex Duo
- Iceland · Íbúfen Extra
- Italy · Buscoactfokus
- Romania · Ibuprofen / Cafeină Hermes
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Base de données publique des médicaments — BDPM (France). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/01affae7-b2ee-44e4-a1e5-2afa1217fb82 GET /v1/drugs/01affae7-b2ee-44e4-a1e5-2afa1217fb82?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cis": "67140828",
"date_amm": "2017-09-20",
"type_amm": "Procédure décentralisée",
"numero_ue": null,
"substance": "CAFÉINE + IBUPROFÈNE",
"statut_amm": "Autorisation active",
"statut_bdm": null,
"forme_pharmaceutique": "comprimé pelliculé",
"voies_administration": "orale",
"etat_commercialisation": "Commercialisée",
"surveillance_renforcee": "Non"
}See everything about caféine + ibuprofène.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.