Germany· DE-A57-66e9b60bff20417e
Topotecan Phares
A topotecan product containing topotecan, registered in Germany by Pharma Resources Gmbh. The same ATC class is registered in 15 of our 19 countries.
Checked against EMA Article 57 (European Union) on
Informational only — not a medical device.
Where it is registered
Topotecan is registered in 15 of 19 countries.
Countries holding a registration under ATC L01CE01 (topotecan), each read from that country’s own register.
- This record: Germany, from EMA Article 57 (European Union)
- 9 of them publish a price we can compare per daily dose
Topotecan · ATC L01CE01
15 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of topotecan costs, country by country.
Normalised to the WHO defined daily dose (1 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Topotecan · price per daily dose (1 mg)
USD · FX 28 Sept 2026
- CH Switzerland$80.29
The record
At a glance
EMA Article 57 (European Union)- Active substance
- Topotecan
- Manufacturer
- Pharma Resources Gmbh
- Country
- Germany (DE)
- ATC code
- L01CE01
- ATC class
- Topotecan
- Defined daily dose
- 1 mg, O
- Reimbursed
- Not published by this register
- Source register
- EMA Article 57 (European Union)
- Last checked
- September 30, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
348 interactions on record for topotecan.
Graded by severity as the source publishes them — 31 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Topotecan · interactions on record
348 records
- 31 severe
- 277 moderate
- 16 minor
- 24 info
Most severe, free to view
- CisplatinL01XA01severe
- CarboplatinL01XA02severe
- OxaliplatinL01XA03severe
- RolapitantA04AD14moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Topotecan in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- FinlandEvotopinBeecham Group plc.
- BelgiumHycamtin 0.25 mgSandoz Pharmaceuticals
- United KingdomHycamtin 0.25mg capsulesSandoz Ltd
- CzechiaHYCAMTINSandoz Pharmaceuticals d.d., Ljubljana
- SwedenHycamtin 0,25 mg Kapsel, hårdSandoz Pharmaceuticals d.d.
- IrelandHYCAMTIN 0.25 mg hard capsulesSandoz Pharmaceuticals d.d.
- NetherlandsHycamtin 0,25mg, Capsule, hardSandoz Pharmaceuticals d.d.
- PolandHycamtinSandoz Pharmaceuticals d.d.
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Topotecan Accord, Topotecan Ebewe
- Belgium · Topotecan Accord Healthcare
- Bulgaria · Топотекан Акорд
- Cyprus · Topotecan Accord, Topotecan Venus
- Czechia · Topotecan Accord
- Denmark · Topotecan "ebewe", Topotecan Accord
- Estonia · Topotecan Accord
- Spain · Topotecán Accord
- Finland · Topotecan Accord, Topotecan Ebewe
- France · Topotecane Accord
- United Kingdom (Northern Ireland) · Topotecan Accord Healthcare, Topotecan Sandoz
- Greece · Topocan, Topotecan Accord
- Croatia · Topotekan Alpha-Medical
- Hungary · Topotecan Accord
- Ireland · Topotecan Accord
- Iceland · Hycamtin, Potactasol
- Italy · Topotecan Ahcl
- Liechtenstein · Hycamtin, Hycamtin 4 Mg Powder For Concentrate For Solution For Infusion
- Lithuania · Topotecan Accord
- Luxembourg · Topotecan Accord Healthcare
- Latvia · Topotecan Ahcl
- Netherlands · Topotecan Accord, Topotecan Hikma
- Norway · Hycamtin, Potactasol
- Poland · Topotecanum Accord
- Portugal · Topotecano Accord, Topotecano Azevedos
- Romania · Topotecan Accord
- Sweden · Topotecan Accord, Topotecan Ebewe
- Slovenia · Topotekan Accord
- Slovakia · Topotecan Accord
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of EMA Article 57 (European Union). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/01755685-cd09-4b2e-a02b-72013e4bf6f2 GET /v1/drugs/01755685-cd09-4b2e-a02b-72013e4bf6f2?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"pzn": null,
"route": "Intravenous Use",
"source": "ema_art57_de",
"ma_number": null,
"substance": "Topotecan",
"atc_from_source": null,
"authorisation_country": "Germany"
}See everything about topotecan.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.