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United States · US · US:80610-115_f310345f-118f-4366-92d8-40ed96ea318b

ZORYVE

Orange BookUNIISPLATC R03DX07

Last synced from FDA National Drug Code directory (United States) on

Identification

ManufacturerArcutis Biotherapeutics, Inc.
CountryUS (United States)
ATC codeR03DX07
Dispensing
ReimbursedNo
SourceFDA National Drug Code directory (United States)
Last synced6/3/2026

Packs · 2

  • ndc11
    8061011560
    1 TUBE in 1 CARTON (80610-115-60) / 60 g in 1 TUBE
  • ndc11
    8061011596
    6 TUBE in 1 CARTON (80610-115-96) / 5 g in 1 TUBE (80610-115-05)

Annotations

UNII (FDA Substance ID)
0P6C6ZOP5U
ROFLUMILAST
RxCUI 1091836
Orange Book
N215985
DailyMed SPL labels
1 version tracked
Raw payload (JSON)
{
  "unii": {
    "unii": "0P6C6ZOP5U",
    "rxcui": "1091836",
    "inchikey": "MNDBXUUTURYVHR-UHFFFAOYSA-N",
    "display_name": "ROFLUMILAST",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "TOPICAL",
  "spl_meta": {
    "ec1bb0d1-f38a-4080-831a-68791d1d1fdb": {
      "match": "brand_token",
      "title": "ZORYVE (ROFLUMILAST) CREAM [ARCUTIS BIOTHERAPEUTICS, INC.]",
      "spl_version": "12",
      "published_date": "2026-02-02"
    }
  },
  "productid": "80610-115_f310345f-118f-4366-92d8-40ed96ea318b",
  "productndc": "80610-115",
  "dosage_form": "CREAM",
  "orange_book": {
    "appl_no": "215985",
    "products": [
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "0.3%",
        "product_no": "001",
        "approval_date": "Jul 29, 2022"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "0.15%",
        "product_no": "002",
        "approval_date": "Jul 9, 2024"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "0.05%",
        "product_no": "003",
        "approval_date": "Oct 4, 2025"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "ROFLUMILAST",
  "proprietary_name": "ZORYVE",
  "active_ingred_unit": "mg/g",
  "application_number": "NDA215985",
  "marketing_category": "NDA",
  "nonproprietary_name": "roflumilast",
  "start_marketing_date": "20240709",
  "active_numerator_strength": "1.5"
}

Related drugs

Other records sharing ATC code R03DX07.

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