Bumex

{
  "unii": {
    "unii": "0Y2S3XUQ5H",
    "rxcui": "1808",
    "inchikey": "MAEIEVLCKWDQJH-UHFFFAOYSA-N",
    "display_name": "BUMETANIDE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "spl_meta": {
    "32dfbea3-eb2b-4070-8605-57ce3e6d5a2f": {
      "match": "brand_token",
      "title": "BUMEX (BUMETANIDE) TABLET [VALIDUS PHARMACEUTICALS LLC]",
      "spl_version": "5",
      "published_date": "2025-09-10"
    }
  },
  "productid": "30698-631_3e4799b2-7621-c0b4-e063-6394a90a47b7",
  "productndc": "30698-631",
  "dosage_form": "TABLET",
  "orange_book": {
    "appl_no": "018225",
    "products": [
      {
        "rs": false,
        "rld": true,
        "te_code": "AB",
        "strength": "1MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**",
        "product_no": "001",
        "approval_date": "Feb 28, 1983"
      },
      {
        "rs": false,
        "rld": true,
        "te_code": "AB",
        "strength": "0.5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**",
        "product_no": "002",
        "approval_date": "Feb 28, 1983"
      },
      {
        "rs": false,
        "rld": true,
        "te_code": "AB",
        "strength": "2MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**",
        "product_no": "003",
        "approval_date": "Jun 14, 1985"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "BUMETANIDE",
  "shortage_reason": "Bumetanide Injection",
  "shortage_status": "current",
  "proprietary_name": "Bumex",
  "active_ingred_unit": "mg/1",
  "application_number": "NDA018225",
  "marketing_category": "NDA",
  "nonproprietary_name": "Bumetanide",
  "start_marketing_date": "19830228",
  "active_numerator_strength": "1"
}