CYCLOSPORINE

{
  "unii": {
    "unii": "83HN0GTJ6D",
    "rxcui": "3008",
    "inchikey": "PMATZTZNYRCHOR-CGLBZJNRSA-N",
    "display_name": "CYCLOSPORINE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "OPHTHALMIC",
  "spl_meta": {
    "f7e4a2f0-ea2a-449b-bc6d-a6ea3d47b850": {
      "match": "brand_token",
      "title": "CYCLOSPORINE EMULSION [UPSHER-SMITH LABORATORIES, LLC]",
      "spl_version": "2",
      "published_date": "2026-05-25"
    }
  },
  "productid": "68180-214_3dade5e6-5243-42a1-b1fa-0fb094e8da5f",
  "productndc": "68180-214",
  "dosage_form": "EMULSION",
  "orange_book": {
    "appl_no": "050790",
    "products": [
      {
        "rs": true,
        "rld": true,
        "te_code": "AB",
        "strength": "0.05%",
        "product_no": "001",
        "approval_date": "Dec 23, 2002"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "0.05%",
        "product_no": "002",
        "approval_date": "Oct 27, 2016"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "CYCLOSPORINE",
  "proprietary_name": "CYCLOSPORINE",
  "active_ingred_unit": "mg/mL",
  "application_number": "NDA050790",
  "marketing_category": "NDA AUTHORIZED GENERIC",
  "nonproprietary_name": "cyclosporine",
  "start_marketing_date": "20220511",
  "active_numerator_strength": ".5"
}