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United States· US:61314-665_238af96f-2f89-9af4-e063-6394a90a9516

Apraclonidine

A apraclonidine product containing apraclonidine hydrochloride, registered in United States by Sandoz Inc. The same ATC class is registered in 14 of our 19 countries.

ATC S01EA03US label

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedApraclonidineATCS01EA03REGISTER NO.US:61314-665_238af96f…PACKS LISTED4CHECKEDSeptember 27, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about apraclonidine hydrochlorideAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Apraclonidine is registered in 14 of 19 countries.

Countries holding a registration under ATC S01EA03 (apraclonidine), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 7 of them publish a price we can compare per daily dose
Search apraclonidine products by name

Apraclonidine · ATC S01EA03

14 / 19 countries

  • Belgiumprice
  • Canada
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
APRACLONIDINE HYDROCHLORIDE
Manufacturer
Sandoz Inc
Country
United States (US)
ATC code
S01EA03
ATC class
Apraclonidine
Defined daily dose
0.3 ml, AT
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 27, 2026

Packs & prices · 4

  • ndc11
    61314-665-05
  • ndc11
    61314-665-10
  • ndc11
    6131466505
    5 mL in 1 BOTTLE (61314-665-05)
  • ndc11
    6131466510
    10 mL in 1 BOTTLE (61314-665-10)

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

77 interactions on record for apraclonidine.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check apraclonidine against other medicinesHow interaction checks work

Apraclonidine · interactions on record

77 records

  • 4 severe
  • 73 moderate

Most severe, free to view

  • ProcarbazineL01XB01severe
  • OzanimodL04AA38severe
  • OzanimodL04AE02severe
  • Methylthioninium chlorideV03AB17severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Apraclonidine in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All apraclonidine products

Authorised across Europe · EMA

The same active substance is authorised in 17 EEA countries. Names it is sold under:

  • Austria · Iopidine
  • Belgium · Iopidine
  • Germany · Iopidine®
  • Denmark · Iopidine
  • Spain · Iopimax
  • Finland · Iopidine
  • France · Iopidine
  • United Kingdom (Northern Ireland) · Apraclonidine, Apraclonidine Essential Pharma
  • Greece · Iopidine
  • Ireland · Iopidine
  • Italy · Iopidine
  • Luxembourg · Iopidine
  • Malta · Iopidine
  • Netherlands · Iopidine
  • Norway · Iopidine
  • Portugal · Iopidine
  • Sweden · Iopidine

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/56942f5a-657d-48f4-b851-1b1c4c863601
GET /v1/drugs/56942f5a-657d-48f4-b851-1b1c4c863601?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "OPHTHALMIC",
  "source": "ndc",
  "strength": "5.75",
  "substance": "APRACLONIDINE HYDROCHLORIDE",
  "productndc": "61314-665",
  "dosage_form": "SOLUTION",
  "dea_schedule": null,
  "strength_unit": "mg/mL",
  "application_number": "NDA020258",
  "marketing_category": "NDA AUTHORIZED GENERIC"
}
API referenceMCP serverPlans

See everything about apraclonidine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console